… evenly across the S protein but were concentrated in two domains: the N-terminal … in the SARS-CoV-2 S protein, we carried out molecular dynamic simulations of the S protein in the …
Y Cai, J Zhang, T Xiao, H Peng, SM Sterling… - Science, 2020 - science.org
… protein for CoV is its spike (S) protein that decorates the virion surface as an extensive crown (hence, “corona”). The protein … Binding through the receptor-binding domain (RBD) in S1 to …
R Yan, Y Zhang, Y Li, F Ye, Y Guo, L Xia, X Zhong… - Cell research, 2021 - nature.com
… S1 consists of the N-terminal domain (NTD), the RBD, … the activation of the S protein of SARS-CoV-2 represents a … of trimeric extracellular domain of the S protein (hereinafter referred to …
A Ali, R Vijayan - Scientific reports, 2020 - nature.com
… were performed to better understand the structural stability and interfacial interactions between the receptor binding domain of the spike (S) protein of SARS-CoV-2 and SARS-…
Z Liu, X Xiao, X Wei, J Li, J Yang, H Tan… - Journal of medical …, 2020 - Wiley Online Library
… In this study, we used systematic comparison and analysis to predict the interaction between the receptor-binding domain (RBD) of coronavirusspikeprotein and the host receptor, …
… domain of the SARS-CoV-2 spikeprotein have evolutionary diverged in comparison to other beta-coronaviruses and particularly SARS-CoV… of mutations, driving SARS-CoV-2 evolution. …
Y He, Y Zhou, P Siddiqui, S Jiang - Biochemical and biophysical research …, 2004 - Elsevier
… inactivated by β-propiolactone elicited high titers of antibodies in the immunized mice and rabbits that recognize the spike (S) protein, especially the receptor-binding domain (RBD) in …
YF Kang, C Sun, Z Zhuang, RY Yuan, Q Zheng, JP Li… - ACS …, 2021 - ACS Publications
… In this study, we designed SARS-CoV-2 vaccine candidates by linking the spikeprotein RBD to a nanoparticle via a covalent ligation strategy. By fusing SpyTag to the C-terminus of RBD…
Y Wu, C Li, S Xia, X Tian, Y Kong, Z Wang, C Gu… - Cell host & …, 2020 - cell.com
… antibodies and apply this methodology to identify SARS-CoV-2-specific … single-domain antibodies target diverse epitopes within the SARS-CoV-2 spikeprotein receptor binding domain (…