Current and Emerging Therapies for COVID-19 in Lung Transplantation

DZP Friedman, NN Pettit, E MacKenzie… - Current Pulmonology …, 2023 - Springer
… Precursors of molnupiravir were previously in development … [29]; in 2018, molnupiravir was
studied and demonstrated activity … dexamethasone doses may be considered in patients with …

The development and validation of a novel LC-MS/MS method for the simultaneous quantification of Molnupiravir and its metabolite ß-d-N4-hydroxycytidine in human …

A Amara, SD Penchala, L Else, C Hale… - … of pharmaceutical and …, 2021 - Elsevier
… pandemic, Molnupiravir (MPV) or EIDD-2801, developed for the treatment of patients with …
this method for determination of MPV and its metabolite in patients with COVID-19 infection. …

[PDF][PDF] FORMULATION AND EVALUATION OF IMMEDIATE RELEASE DRUG DELIVERY OF MOLNUPIRAVIR TABLET

PB Pawal, AS Khamat, AU Gadekar - 2022 - wjpr.s3.ap-south-1.amazonaws.com
… antivirals molnupiravir for the outpatient treatment of mild to moderate COVID-19 patients
who … with early SARS-CoV-2: a Phase I, open-label, dose-escalating, randomized controlled …

Pandemic COVID-19, an update of current status and new therapeutic strategies

A Vitiello, R La Porta, U Trama, F Ferrara, A Zovi… - Naunyn-Schmiedeberg's …, 2022 - Springer
… of molnupiravir in patients with COVID-19 (Table 1). The results of the ongoing trial may
further bring more clarity, especially on the efficacy of Molnupiravir in the new variant Omicron. …

Molnupiravir for the treatment of COVID-19 outpatients: An updated meta-analysis

HA Cheema, SA Rab, M Butt, U Jafar, A Shahid… - Journal of Microbiology …, 2024 - Elsevier
… To the best of our knowledge, this is the largest meta-analysis to date that evaluated the
effectiveness of molnupiravir in COVID-19 patients and also stratified according to the status of …

Medications for early treatment of COVID‐19 in Australia

A Polkinghorne, JM Branley - Medical Journal of Australia, 2022 - Wiley Online Library
patients receiving molnupiravir treatment are advised to use contraceptives during treatment
and for 3 months for men and 4 days for women after the last dose… of care and escalation to …

[PDF][PDF] Antiviral treatment in COVID-19 outpatients: a systematic review of randomized controlled trials

DS Budi, P Oktavian, TP Asmarawati, P Lestari… - Acta Med …, 2022 - researchgate.net
… First, this study mainly discusses Favipiravir and molnupiravir … for oral treatment of COVID-19
in nonhospitalized patients. N … A phase 2a clinical trial of molnupiravir in patients with …

[HTML][HTML] … assay and trace level genotoxic impurities quantification of SARS-CoV-2 inhibitor-Molnupiravir in its pure and formulation dosage forms using fractional …

S Nakka, SK Muchakayala, SBM Surya - Results in Chemistry, 2023 - Elsevier
… LC-MS method for the active drug and both PGTIs in Molnupiravir. … Optimal dose and
safety of molnupiravir in patients with early SARS-CoV-2: a Phase I, open-label, dose-escalating, …

Vaccination and antiviral treatment reduce the time to negative SARS-CoV-2 Swab: a real-life study

A De Vito, G Moi, L Saderi, MV Puci, A Colpani, L Firino… - Viruses, 2023 - mdpi.com
patients who died or were discharged with a positive swab were excluded from the study.
A total of 175 patientspatients treated with remdesivir, molnupiravir, and nirmatrelvir/ritonavir. …

[HTML][HTML] Commentary Potential Enhancement by 3-Deazauridine of the Antiviral Activity of Molnupiravir in Patients with COVID-19

RL Momparler - Advances in Infectious Diseases, 2023 - scirp.org
molnupiravir to patients with COVID-19. … dose of molnupiravir, the duration of the infusion
of 3DU should be about 6 h to obtain maximum incorporation of NHC into viral RNA. In patients