Intracellular drug delivery using low-frequency ultrasound: quantification of molecular uptake and cell viability

K Keyhani, HR Guzmán, A Parsons, TN Lewis… - Pharmaceutical …, 2001 - Springer
… To guide design and optimization of ultrasound parameters useful for drug delivery, we used
flow cytometry to measure molecular uptake and viability of DU145 prostate cancer cells as …

Endocytosis in cellular uptake of drug delivery vectors: Molecular aspects in drug development

Z Kaźmierczak, K Szostak-Paluch, M Przybyło… - Bioorganic & Medicinal …, 2020 - Elsevier
… are available for drug delivery by large nanocarriers. We focus on molecular aspects of the
… Here we present a review of cellular uptake pathways important in the delivery of liposomes …

Arginine-rich molecular transporters for drug delivery: role of backbone spacing in cellular uptake

JB Rothbard, E Kreider, CL VanDeusen… - Journal of medicinal …, 2002 - ACS Publications
… to determine the structural requirements for cellular uptake of guanidine rich transporters
and to use this information to develop more effective molecular transporters. The importance of …

Drug delivery with polymeric nanocarriers—cellular uptake mechanisms

LC Nelemans, L Gurevich - Materials, 2020 - mdpi.com
… we survey drug delivery systems based on various polymeric nanocarriers, their uptake
is observed as the main uptake pathway, the integrity of a drug-loaded nanocarrier upon its …

Nanocarriers' entry into the cell: relevance to drug delivery

H Hillaireau, P Couvreur - Cellular and molecular life sciences, 2009 - Springer
… Depending on the cellular uptake and … drug delivery applications. Nevertheless, various
strategies are being actively investigated in order to tailor nanocarriers able to deliver anticancer …

Cellular uptake of nanoparticles versus small molecules: a matter of size

J Mosquera, I García… - Accounts of chemical …, 2018 - ACS Publications
… in drug delivery and sensing applications. The Account ends with a “Conclusions and
Outlook” section, where general lessons and future directions toward further advancements are …

Identification of multiple cellular uptake pathways of polystyrene nanoparticles and factors affecting the uptake: Relevance for drug delivery systems

R Firdessa, TA Oelschlaeger, H Moll - European journal of cell biology, 2014 - Elsevier
… Hence, understanding the uptake mechanisms and cellular interactions of nanoparticles at
… the uptake mechanisms of polystyrene nanoparticles and factors affecting their uptake in …

Functionalized single-walled carbon nanotubes: cellular uptake, biodistribution and applications in drug delivery

Z Li, ALB de Barros, DCF Soares, SN Moss… - International journal of …, 2017 - Elsevier
… of drug delivery by functionalized SWNT carriers, diving into the cellular uptake mechanisms,
biodistribution of the delivery … of SWNT-based molecular delivery systems has been studied …

Cell Uptake and in Vitro Toxicity of Magnetic Nanoparticles Suitable for Drug Delivery

UO Häfeli, JS Riffle, L Harris-Shekhawat… - Molecular …, 2009 - ACS Publications
… For in vivo magnetic drug delivery to the eye, a most important factor is the nontoxicity of the
… Furthermore, the treatment of intraocular tumors is another potential drug delivery target, and …

Endocytic mechanisms for targeted drug delivery

LM Bareford, PW Swaan - Advanced drug delivery reviews, 2007 - Elsevier
… This approach is termed synthetic receptor targeting (SRT) and currently adapted for high
affinity binding of targeting molecules and clathrin-dependent uptake. SRT would allow for the …