… transporters in human drug disposition by reviewing recent advances in the pharmacogenomics
of OATP transporters … the expression of drug-metabolizing enzymes, rifampicin has been …

… Ideally, the contributions of these enzymes and transporters to drug disposition can be
predicted from in vitro experiments and in silico modeling in discovery or early development, and …

… Actually, ABC transporters act in synergy with drug-metabolizing enzymes to protect the …
transporters in drug disposition and more precisely their role in drug distribution to the heart. …

… for the study of efflux transporter activity and of transporter-enzyme interplay and were …
together with selective transporter inhibitors. The fate of ABC efflux transporters in isolated and …

… of pulmonary drug disposition in … of drug disposition in different disease states, and
developing novel approaches to study lung-specific drug transporters and metabolizing enzymes. …

… drug therapy. This review discusses drug disposition of anticancer agents and the … of
phenotyping probes for phase I, II metabolic enzymes, and drug transporters in oncology. …

… drug metabolizing enzymes; the interplay of enzyme-transporter proteins; and lack of knowledge
on enzyme … in the intestine, CYP3A is the enzyme that is frequently implicated in human …

… exists between intestinal drug metabolising enzymes and apical efflux transporters, a …
mediate drug transport, since these proteins can have a major impact on drug disposition and drug …

… Although some changes in drug disposition profiles were observed, data appear to be … in
a broad induction of transporters and enzymes involved in drug detoxification, such as CYP3A4…

… insight, potential developmental patterns of membrane transporters in animals are likely to
differ from those in humans, as studies on drug metabolizing enzymes (DMEs) have shown […