… discovery of new therapies against COVID-19. In this article, … regarding efficacy of repurposed
drugs against COVID-19 and … COVID-19 epidemiology, and then have discussed drug …

… mortality in patients with severe COVID-19. In addition, convalescent plasma … COVID-19.
There is currently no single worldwide approved therapeutic option for patients with COVID-19 …

… of these newly developed drugs on COVID-19. Experience with previous virus pandemics
has shown us that developing an ample repertoire of antiviral drugs with different targets will …

… COVID-19 patients in an inflammatory state and their interaction with drug transporters and
drug-… permit the individualization of these drugs, thereby enhancing the safety and efficacy. …

… In the United States, the most promising drug therapy thus far has been remdesivir (GS-…
and Drug Administration to allow emergency use access of the drug for COVID-19 treatment on …

… The experimental antiviral drug remdesivir (manufactured by Gilead) was granted … US Food
and Drug Administration in May 2020 for patients hospitalized with severe COVID-19. At the …

… COVID-19 in the United States (14). In order to evaluate the efficacy and safety of the drug in
patients with COVID-19… some other drugs may have potential efficacy in treating COVID-19. …

… efficacy in treating COVID-19. However, its emergence has also led to a large number of
clinical trials evaluating drug … to move beyond traditional drug screening and repurposing by …

… RCTs) provide information on drug tolerability and, most importantly, efficacy. RCTs are
considered the gold standard of evidence generation on drug efficacy because randomization of …

… on the available treatments for COVID-19 virus in the past year… the safety and efficacy of
experimental treatments of COVID-19. … be promising drugs in the treatment of COVID-19 patients. …