… 2022) where transporter-mediated disposition of drug molecules has been captured using
PBPK modeling Thus, this review aims to provide a comprehensive insight into the state-of-the…

… pharmacokinetic herb-drug interactions. A review of the literature reporting herbal medicines,
their effects and documented interactions with conventional drugs was conducted between …

Mounting evidence demonstrates that CYP2B6 plays a much larger role in human drug
metabolism than was previously believed. The discovery of multiple important substrates of …

… Once a CYP enzyme is combined with a certain xenobiotic compound, its catalytic activity
may be decreased, which will trigger drug-drug interactions when it is coadministrated with …

… for DDIs and supplement-drug interactions between NSAIDs and other drugs or herbal and
… a significant competitive site underlying the comprehensive DDIs between MTX and NSAIDs, …

Translational research is an emerging discipline that aims to fill the gap through the whole
pipeline from bench to bedside. This review highlights the importance and urgency of …

… body systems on the drug. As we focus on direct interaction with biological pathways …
On the other hand, it is known that many marketed drugs interact with this receptor. Indeed, …

… Factors such as precorneal fluid drainage, drug binding to tear proteins, systemic drug
absorption, corneal factors, melanin binding, and drug metabolism render ocular delivery …

… Drug Interactions is, as ever, to inform busy doctors, pharmacists, nurses and other healthcare
professionals of the facts about drug interactions… If you need some insight into the general …

… to the active metabolite, drug–drug interactions and receptor polymorphisms. Increased
loading … The aim of this article is to provide a comprehensive and current review of clopidogrel …