… The purpose of the review for the investigation of influence of drugs on the marker
substrates of CYP isoenzymes was to determine the presence or absence of any effect on …

… The principle of isoform specificity (drugs metabolized by the same iso‐form should exhibit
interactions with the same inhibitors) was applied to the interactions of PHT with 17 inhibitors …

… The cytochrome P450 (P450 or CYP) isoenzymes are the population, allowing classification
of … (99) who reported that changes in the inhibitory effect of several P450 isozymes in a study …

… Identity of the CYP isoenzymes involved in riluzole biotransformation was established using
… expressed human CYP isoenzymes from transfected cell lines and yeast and isoenzyme-…

… isoenzymes of Cyp-450 are known to exist, four isoenzymes are predominantly responsible
for the majority of drug interactions: … Some drugs are metabolized by more than one enzyme (…

… for drug-drug interactions between clobazam and various CYP isoenzyme substrates, … been
reported to prolong the elimination of drugs metabolized by CYP (eg, phenytoin, diazepam, …

… The present system of nomenclature for the various CYP isozymes employs a three-tiered …
drugs in humans belong to the CYP families 1–4 and more than 30 human CYP isozymes …

… in ARV drug interactions and are metabolised by CYP isoenzymes. Because … CYP isoenzymes,
they often interfere with the metabolism of several drugs eliminated by CYP isoenzymes…

… CYP2D6 and other isoenzyme systems, … (CYP) system. In particular, the importance of
CYP2D6, the most widely studied of the CYP isoenzymes, in antidepressant drug interactions is …

… to result in an interaction when given with virtually any drug, are isozyme-selective in their …
the same CYP isozyme mediates the biotransformation of two disparate drugs, the drugs can …