… of human OATP family members, the role of human OATPs in drug–drug interactions, and the
… of genetic variations in SLCO genes encoding OATP proteins are the focus of this chapter. …

… we will focus on the hepatic OATP family members OATP1B1, OATP1B3, and OATP2B1, as
well as on the hepatic OCT family member OCT1, their role in drug-drug interactions, and on …

… drug–drug interactions at hepatocellular drug transporters. Cyclosporine inhibits hepatocellular
uptake of rosuvastatin by OATP1B1, … the ABC family, contribute to the export of drugs and …

… drugdrug interactions. This review describes several examples of pharmacokinetic drug
interaction, … form a single protein family—the OATP family. In humans, hOATP was cloned from a …

… (OATP) family have been shown to interact with a variety of … the role of OATP1B1 in
gemfibrozil–drug interactions with statins. … interaction into prediction of gemfibrozil–drug …

… Hepatic uptake carriers of the organic anion-transporting peptide (OATP) family of solute …
many drugs and potentially associated drug-drug interactions. The gemfibrozil-statin interaction …

… with drugs that are substrates for human OATP proteins. In this … in transporter genes encoding
human OATP family members and … -drug interactions. Variations in genes encoding uptake …

… and Meier, PJ: Organic anion transporting polypeptides of the OATP/SLC21 family:
phylogenetic classification as OATP/SLCO superfamily, new nomenclature and molecular/functional …

… , as well as the impact of drug interactions in vivo, is knowledge of … ; in this case, of OATPs
in the human liver. Because deep … studies on OATP1B1 mediated drug interactions have been …

… the human OATP family, discussing clinically relevant consequences of altered OATP function.
… data on the role of OATPs in ADME and in drug–drug interactions, especially focusing on …