过去一年中添加的文章,按日期排序

DISEASE-, NATURAL PRODUCT-, AND DRUG-MEDIATED PHARMACOKINETIC INTERACTIONS OF HEPATIC ORGANIC ANION TRANSPORTING …

B Bechtold - rex.libraries.wsu.edu
15 天前 - … of transporters encoded by the SLCO gene family. OATP1Bs are located on the …
-drug interaction. Unfortunately, rodent models express a single ortholog to human OATP1B1

Rifampin-and silymarin-mediated pharmacokinetic interactions of exogenous and endogenous substrates in a transgenic OATP1b mouse model

BJ Bechtold, KD Lynch, VO Oyanna… - Molecular …, 2024 - ACS Publications
107 天前 - … (OATPs in humans; Oatps in rodents) are a superfamily of transporters involved in
the pharmacokinetics of many drugsOATPs represent a large family of uptake transporters …

OATP Overexpressed Cells and Their Use in Drug Uptake Studies

L Wang, Z Xie, Y Tu, M Hu - Oral Bioavailability and Drug …, 2023 - Wiley Online Library
275 天前 - … polypeptides (OATPs) are an important family of uptake … of OATPs in pharmacokinetics
and drugdrug interactions … By knowing whether and which OATPs are involved in the …

Cryo-EM structures of human organic anion transporting polypeptide OATP1B1

Z Shan, X Yang, H Liu, Y Yuan, Y Xiao, J Nan… - Cell Research, 2023 - nature.com
309 天前 - … transporting polypeptide (OATPs) family function as transporters … drugdrug
interactions (DDIs) involving OATP1B1. However, the structure and working mechanism of OATPs