… OATPs (members of the solute carrier family SLCO), the organic anion transporters or OATs
(members of the SLC22 family)… to drug–drug interaction (DDI) on drug transporters as well as …

… drugs. This review will summarize in particular clinically observed drug-drug interactions …
uptake transporters [organic anion transporting polypeptides (OATPs)], or to inhibition of …

… Organic anion transporting polypeptides (OATP) form a family … Of the 11 human OATP
transporters, OATP1B1, OATP1B3 and … of OATP1B1 is involved in the drug–drug interactions of …

… drugs can cause unintended and unwanted outcomes which may lead to significant harm in
some cases. The risk of drug interactions increases with number of drugs … of this family are …

… /SLC21 (OATP) and SLC22 (OCT/OAT) family of solute carriers and … drugs and
transporter-mediated drug-drug interactions and we especially focus on the uptake transporters …

… ) family, are localized in organs involved in drug elimination, … human OATP transporters that
comprise 6 families (OATP1-6), OATP1A2 and OATP2B1 are reportedly expressed in human …

… OATP transporters as well as studies investigating the roles of OATP transporters in drug
interactions… The genes encoding human OATP1 family members, OATP1A2, OATP1B1, …

… ) is the third human OATP family member expressed in … To this day, only one study describing
drug–drug interactions with this … important family of drug transporters is the SLC22 family (…

… To gain more insights into the role of uptake transporters for drug interactions, we … drugs
interact with the transport of drugs, mediated by the hepatic uptake transporters OATP1B1 (gene …

… supported the idea that OATP1B1 is a predominant … OATP1B1-mediated drug-drug interaction,
we checked the inhibitory effects of various drugs on the pitavastatin uptake in OATP1B1-…