JT August, F Murad, MW Anders, JT Coyle, A Li - 1997 - books.google.com
… for drug-druginteractions. The chapters in this book present a comprehensive review of the scientific and regulatory aspects of drug-druginteractions … The topics covered include drug …
L Zhang, Y Zhang, JM Strong, KS Reynolds… - Xenobiotica, 2008 - Taylor & Francis
… a regulatory viewpoint on transporters and their potential role in drug–druginteractions. It first … transporters has increased dramatically over the years because of the scientific progress in …
L Zhang, Y Zhang, P Zhao, SM Huang - The AAPS journal, 2009 - Springer
… hampered by unknown factors to be discovered as science evolves and as the knowledge of the drug accumulates. Therefore, the ability to quantitatively predict the magnitude of in vivo …
TD Bjornsson, JT Callaghan, HJ Einolf, V Fischer… - Drug metabolism and …, 2003 - ASPET
… Such data are useful in the prediction of pharmacokinetic drug-druginteractions and interpatient variability in drug exposure. The science underlying P450 reaction phenotyping has …
T Iwatsubo - Drug metabolism and pharmacokinetics, 2020 - Elsevier
… ones, the common points and differences among the US, Europe (EU) and Japan are discussed and shared from the viewpoint of scientific evaluation and international harmonization. …
DN Juurlink - Journal of the American Pharmacists Association, 2004 - japha.org
… In this Viewpoint article, I discuss some of these obstacles, and suggest strategies by which … However, the scientists who study the issue are unlikely to alter how they disseminate their …
S Sudsakorn, P Bahadduri, J Fretland… - Current drug …, 2020 - ingentaconnect.com
… Drug-druginteractions (DDI) are key aspects of drug metabolism and pharmacokinetic considerations and are studied in both preclinical development and throughout the clinical …
SE Leucuta, L Vlase - Current clinical pharmacology, 2006 - ingentaconnect.com
… analyzing data from a druginteraction study. … drug-druginteractions may help in a better management of pharmacotherapy including the avoidance of clinically relevant druginteractions…
… scientists have exploited the computerized modeling methods in different aspects of pharmaceutical sciences including drug … and personalized medicine viewpoints, effective standard …