JA Roberts, R Norris, DL Paterson… - British journal of clinical …, 2012 - Wiley Online Library
… Target concentration intervention is suggested to enable more accurate doseadjustment because it uses all relevant data on the patient and disease [13]. Such an approach would …
… exposure to drugs for personalized doseadjustment is of … samples have been used for drugmonitoring, which only poses … may improve the feasibility of therapeutic drugmonitoring. …
JS Kang, MH Lee - The Korean journal of internal medicine, 2009 - ncbi.nlm.nih.gov
… The assay results should be available quickly, preferably within 24 h of receiving the sample, as the most important uses of the measurements are during dosageadjustments and in …
F Lemaitre, K Budde, T Van Gelder… - … Drug Monitoring, 2023 - journals.lww.com
… for therapeutic drugmonitoring of ISDs and dosing recommendations when … cyclosporine dosage should be reduced to 20% of the initial dosage during the antiviral treatment. Dosages …
JJ Lee, JH Beumer, E Chu - Cancer chemotherapy and pharmacology, 2016 - Springer
… 5-FU dosing with the main goals of increasing clinical efficacy while reducing drug-associated … doseadjustment of 5-FU based on plasma 5-FU drug levels is feasible and that PK-based …
E Cuvelier, H Khazri, C Lecluse, B Hennart, A Amad… - Pharmaceuticals, 2023 - mdpi.com
… results of therapeutic drugmonitoring and pharmacogenetic … drug management prompted by therapeutic drugmonitoring … drug concentration based on metabolic status with the dose …
M Briki, P André, Y Thoma, N Widmer, AD Wagner… - Pharmaceutics, 2023 - mdpi.com
… for adjustment is then delayed to the next infusion, if any. Moreover, optimal adjustment could … Current TDM practices are mainly suited for a posteriori doseadjustment, which is …
ME de Jonge, ADR Huitema, JHM Schellens… - Clinical …, 2005 - Springer
… , the doseadjustment can be easily derived based on a representative plasma concentration. In several studies, mostly involving fluorouracil, such a dose-adjustment scheme or …
… , the elderly, patients with associated diseases, drug formulation changes); (5) when a … an interacting drug is added or removed); (6) to guide doseadjustments for AEDs with dose-…