Therapeutic drug monitoring can improve linezolid dosing regimens in current clinical practice: a review of linezolid pharmacokinetics and pharmacodynamics

GG Rao, R Konicki, D Cattaneo… - … drug monitoring, 2020 - journals.lww.com
… need for linezolid dose adjustments have also been identified. Therapeutic Drug Monitoring
(TDM… of an individual patient and helps adjust the dosing regimen to maximize efficacy while …

Therapeutic drug monitoring in child and adolescent psychiatry

KM Egberts, C Mehler-Wex, M Gerlach - Pharmacopsychiatry, 2011 - thieme-connect.com
… handling, since the dose recommendations for adults can not … Therapeutic Drug Monitoring
(TDM) is an established and … drug treatment in the individual patient by dose adjustments

Therapeutic drug monitoring of mycophenolic acid

LM Shaw, M Figurski, MC Milone, J Trofe… - Clinical Journal of the …, 2007 - journals.lww.com
… compared with empiric dosing. The design of both of these investigations more nearly
mimics the routine clinic setting in that specific guidelines for dosage adjustment were provided …

Does beta-lactam pharmacokinetic variability in critically ill patients justify therapeutic drug monitoring? A systematic review

FB Sime, MS Roberts, SL Peake, J Lipman… - Annals of intensive …, 2012 - Springer
… To our knowledge, no studies have adjusted antibiotic doses based on presumed ISF
distribution. Problematic to such an approach is that antibiotic concentrations appears to vary …

Area-under-the-curve versus trough level monitoring of cyclosporine concentration: critical assessment of dosage adjustment practices and measurement of clinical …

J Grevel - Therapeutic drug monitoring, 1993 - journals.lww.com
… Area-under-the-curve (AUC) monitoring affords better control … A linear pharmacokinetic
model for CsA dosage adjustment … the relationship between oral dose rate and average steady-…

Therapeutic drug monitoring in HIV infection: current status and future directions

D Back, G Gatti, C Fletcher, R Garaffo, R Haubrich… - Aids, 2002 - journals.lww.com
… This study is an example of dose adjustments based on plasma concentrations. If the
plasma levels had not been measured, the regimen components might have been needlessly …

Dose adjustment guidelines for medications in patients with renal impairment: how consistent are drug information sources?

A Khanal, RL Castelino, GM Peterson… - Internal medicine …, 2014 - Wiley Online Library
… in dosing information may augment the problem of dosing … provide recommendations for
dosage adjustment in renal … dosage adjustment in renal impairment among different drug

Therapeutic drug monitoring of cyclosporine: 20 years of progress

BD Kahan - Transplantation proceedings, 2004 - Elsevier
… development of a Bayesian forecasting technique that predicts dose adjustments necessary
to achieve the optimal drug regimen during the critical period immediately posttransplant. …

Therapeutic drug monitoring of antiepileptic drugs in epilepsy: a 2018 update

PN Patsalos, EP Spencer, DJ Berry - Therapeutic drug monitoring, 2018 - journals.lww.com
… TDM provides a pragmatic approach to epilepsy care, in that bespoke dose adjustments
are undertaken based on drug concentrations so as to optimize clinical outcome. For the older …

Is there a role for therapeutic drug monitoring of new anticonvulsants?

E Perucca - Clinical pharmacokinetics, 2000 - Springer
… because therapeutic drug monitoring (TDM) is considered unfavourable for the marketing of
a new … or multiple drug treatment in whom dosage adjustment is necessary because of dose-…