Therapeutic drug monitoring is essential for intravenous busulfan therapy in pediatric hematopoietic stem cell recipients

R Malär, F Sjöö, K Rentsch, M Hassan… - Pediatric …, 2011 - Wiley Online Library
… In order to identify a population at risk for dose adjustment, we analyzed different groups
of patient characteristics, eg, weight, age, and underlying disease. None of the compared …

Therapeutic drug monitoring-guided dosing of busulfan differs from weight-based dosing in hematopoietic stem cell transplant patients

B Salman, M Al-Za'abi, M Al-Huneini… - … /oncology and stem …, 2017 - journals.lww.com
… the dependency on therapeutic drug monitoring (TDM) of Bu. We compared the Bu dose given
using TDM with … Similarly, dose adjustments were made possible for Dose 5, Dose 9, and …

Evaluation of dosage adjustment in patients with renal impairment

PI Pillans, PG Landsberg, AM Fleming… - Internal medicine …, 2003 - Wiley Online Library
… The aim of the present study was to determine whether appropriate dosage adjustments
are made for drugs with a high fractional renal excretion (f e ) and relatively narrow therapeutic …

Evolution of the therapeutic drug monitoring of cyclosporine

F Citterio - Transplantation proceedings, 2004 - Elsevier
… workers 39 compared the clinical benefits of Neoral dose monitoring with C0 versus C2
levels, during 7 months' follow-up. Neoral dose adjustment was compared with C0 (range 100 to …

[HTML][HTML] Evaluation of applying drug dose adjustment by physicians in patients with renal impairment

AM Alahdal, AA Elberry - Saudi Pharmaceutical Journal, 2012 - Elsevier
… is unchanged, then the area under the curve will be the same as in the normal case, but
with higher trough values which are what is customarily measured in drug monitoring. This can …

Standards of laboratory practice: antidepressant drug monitoring

MW Linder, PE Keck Jr - Clinical chemistry, 1998 - academic.oup.com
drugs excellent candidates for improved therapeutic efficacy through therapeutic drug
monitoring. … requires careful monitoring of lithium concentration and dose adjustment when these …

Best practice in therapeutic drug monitoring

AS Gross - British journal of clinical pharmacology, 2001 - Wiley Online Library
drug monitoring services have usually been set up within large hospitals and this article
focuses on monitoring of … and Ray Morris, dations for dosage adjustment, and seek their further …

Linezolid dose adjustment according to therapeutic drug monitoring helps reach the goal concentration in severe patients, and the oldest seniors benefit more

Y Xu, X Yang, P Liang, C Qu - BMC Infectious Diseases, 2023 - Springer
… Due to the deterioration of organ function, the elderly are prone to drug accumulation and
require dose adjustment [18]. However, experience with repeated monitoring of linezolid …

Personalized therapy for mycophenolate: consensus report by the international association of therapeutic drug monitoring and clinical toxicology

S Bergan, M Brunet, DA Hesselink… - … drug monitoring, 2021 - journals.lww.com
doses were recommended by the manufacturer. Awareness of the potential for a more
personalized dosing … the curve based on the measurement of drug concentrations in only a few …

Individual 5-fluorouracil dose adjustment via pharmacokinetic monitoring versus conventional body-area-surface method: A meta-analysis

R Yang, Y Zhang, H Zhou, P Zhang… - … drug monitoring, 2016 - journals.lww.com
… PK-monitored group and BSA-based group to provide a basis for clinical decision making.
Our analysis shows that 5-FU dose adjustment … than fixed 5-FU dosing based on BSA. To our …