… protein drugtargets of SARS-CoV-2 and their structures, including the drugtarget class and its … We have also discussed several drug discovery approaches and associated protein drug …
… of action may be a practical therapeutic strategy for the treatment of severe COVID-19. … therapeutics against SARS-CoV-2. This review highlights the anti–SARS-CoV-2drugtargets and …
P Chellapandi, S Saranya - Medicinal Chemistry Research, 2020 - Springer
… of candidate repurposable drugs and potential drug combinations targetingSARS-CoV-2 using disease-related molecular networks. A systematic drug repurposing approach has been …
A Mishra, AS Rathore - Journal of Biomolecular Structure and …, 2022 - Taylor & Francis
… RNA polymerase is treated as a principal target for the SARS-CoV2. Its similarity with other viruses allows us to test the existing antiviral molecule against COVID19. Nucleotide analogs, …
C Wu, Y Liu, Y Yang, P Zhang, W Zhong… - … Pharmaceutica Sinica B, 2020 - Elsevier
… and targets for further in vitro and in vivo studies of SARS-CoV-2, new insights for those … drug repositioning candidates and targets for further in vitro and in vivo studies of SARS-CoV-2…
… SARS-CoV-2drugtarget was screened for probable drug … and SWEETLEAD drug database (Centre for Drug Evaluation … used for drug repurposing studies against the drugtarget 3CL …
… confidence protein–protein interactions between SARS-CoV-2 and human proteins. Among … targeted by 69 compounds (of which, 29 drugs are approved by the US Food and Drug …
… Identification of existing drugstargetingSARS-CoV-2 human host factors. To identify small molecules targeting human proteins in the SARS-CoV-2 interactome, we sought ligands …
Y Zhou, Y Hou, J Shen, Y Huang, W Martin, F Cheng - Cell discovery, 2020 - nature.com
… (2019-nCoV, also known as SARS-CoV-2), lead global epidemics with high morbidity and … drugstargeting 2019-nCoV/SARS-CoV-2. Drug repurposing, representing as an effective drug …