… The similarity between S protein of SARS-CoV-2, SARS CoV, and MERS CoV is that in
all … The trimeric spike glycoprotein (S) of SARS-CoV-2 is a key target for virus neutralizing …

… ideal drug target because, to the best of our knowledge, no human host-cell proteases are
known with this substrate specificity.59, 60, 61 Viral proteases are well validated drug targets …

… inhibitors, Nsp12-RdRp has been used as a very important drug target. In principle, targeted
inhibition of Nsp12-RdRp could not cause significant toxicity and side effects on host cells, …

… protein drug targets of SARS-CoV-2 and their structures, including the drug target class and
its … We have also discussed several drug discovery approaches and associated protein drug …

… , such as viral proteins of SARS-CoV-2. We … SARS-CoV-2 with the hope that effective drugs
can be developed based on these AI-proposed drug candidates and act against SARS-CoV-2…

… for SARS-CoV-2 host interactome exploration and drug (target) … -protein interactions, and
drug-target interactions. It allows … In summary, with CoVex, we found a new drug target that …

… A multitarget treatment approach with synergistic drug combinations containing different …
against SARS-CoV-2. This review highlights the anti–SARS-CoV-2 drug targets and therapeutic …

… NSP13 can be considered as a drug target against COVID-19. (94) … to SARS-CoV-2 replication
cycle targets and drugs in PubMed, finding that the SARS-CoV-2 replication cycle targets …

… For the discovery of novel drug-like compounds, we screened compounds structurally
similar to Galidesivir that may target SARS-CoV-2 RdRp as an antiviral agent. The best hits—…

… by the SARS-CoV-2 RdRp, a well-established drug target for … -approved hepatitis C drug)
is incorporated by SARS-CoV-2 … an inhibitor of the SARS-CoV and SARS-CoV-2 RdRp using …