Endothelial activation and dysfunction in COVID-19: from basic mechanisms to potential therapeutic approaches

Y Jin, W Ji, H Yang, S Chen, W Zhang… - Signal transduction and …, 2020 - nature.com
… that endothelial activation and dysfunction participate in COVID-19 pathogenesis by altering
the … and molecular mechanisms of endothelial activation and dysfunction during COVID-19

The mechanism of multiple organ dysfunction syndrome in patients with COVID19

W Zhao, H Li, J Li, B Xu, J Xu - Journal of medical virology, 2022 - Wiley Online Library
… Researchers 3 analyzed the clinical characteristics of 41 COVID-19 patients and … COVID-19
patients, 11% exhibited short term deterioration and later died of multiple organ dysfunction

Endothelial dysfunction in COVID-19: a unifying mechanism and a potential therapeutic target

P Ambrosino, IL Calcaterra, M Mosella, R Formisano… - Biomedicines, 2022 - mdpi.com
… of COVID-19, the aim of this review is to summarize the pathophysiology of endothelial
dysfunction in this … strategies targeting endothelial dysfunction as an attractive therapeutic option. …

Endothelial dysfunction in COVID-19: an overview of evidence, biomarkers, mechanisms and potential therapies

S Xu, I Ilyas, J Weng - Acta Pharmacologica Sinica, 2023 - nature.com
… contribution of endothelial dysfunction to COVID-19 and its sequelae, we overviewed, in this
article, the pivotal role and mechanistic basis of endothelial dysfunction in COVID-19 and its …

Endothelial dysfunction and immunothrombosis as key pathogenic mechanisms in COVID-19

A Bonaventura, A Vecchié, L Dagna… - Nature Reviews …, 2021 - nature.com
… is a typical feature and may contribute to coagulopathy, yet liver impairment in COVID-19 is
main approaches that are being explored to address these features of COVID-19 (Table 1). …

Endothelial Dysfunction, Inflammation, and Oxidative Stress in COVID19Mechanisms and Therapeutic Targets

A Fodor, B Tiperciuc, C Login… - Oxidative medicine …, 2021 - Wiley Online Library
… New observations show that COVID-19 is an endothelial disease, and the consequent …
endothelial dysfunction, inflammation, and oxidative stress in the COVID-19 pathogenesis …

Investigating the possible mechanisms of autonomic dysfunction post-COVID-19

M Jammoul, J Naddour, A Madi, MA Reslan… - Autonomic …, 2023 - Elsevier
… -COVID is largely unknown. As such, this review aims to highlight the potential mechanisms
by which AD occurs in patients with long COVID. The first proposed mechanism includes the …

Olfactory dysfunction in COVID-19: new insights into the underlying mechanisms

R Butowt, K Bilinska, CS von Bartheld - Trends in Neurosciences, 2023 - cell.com
… The mechanisms of olfactory dysfunction in COVID-19 are still unclear. In this review, we
examine potential mechanisms … This mechanism is consistent with the rapid loss of smell with …

Viral endothelial dysfunction: A unifying mechanism for COVID-19

M Prasad, M Leon, LO Lerman, A Lerman - Mayo Clinic Proceedings, 2021 - Elsevier
… -induced endothelial dysfunction as the underlying pathophysiologic mechanism leading
to the multisystem involvement seen with severe acute respiratory syndrome coronavirus 2 (…

Endothelial dysfunction in COVID-19: potential mechanisms and possible therapeutic options

MC Pelle, I Zaffina, S Lucà, V Forte, V Trapanese… - Life, 2022 - mdpi.com
COVID-19, in this review, we will attempt to clarify the underlying pathophysiological mechanisms.
… The main mechanisms involved in ED in different organs are summarized in Table 1. …