… between the immune responses of the lung in children and adults, immune dysregulation
and … Dysregulation in the immune system can lead to an unappropriated local and systemic …

… of lymphocytes reveals the role of dysregulated immune responses in the pathogenesis of …
in the body, resulting in several immune responses to impair the corresponding organs. NLR …

… It is unclear whether dysregulated signaling though ICOS results in … However, in dysregulated
immune responses, TFH cells have … In this context, dysregulated TFH cells producing large …

… In order to understand the immune responses during the disease, we performed single-cell
mRNA sequencing (scRNA-seq) of patient peripheral blood mononuclear cells (PBMCs). …

… involved in the alterations of innate and adaptive immunity in COVID-19 patients, with the …
inflammatory syndrome and evade host antiviral immune responses. In this review, we present …

… COVID-19 disease severity correlates with an excessive proinflammatory immune response
and profound lymphopenia. Inflammatory responses according to disease severity were …

The prognosis of severe COVID-19 patients has motivated research communities to uncover
mechanisms of SARS-CoV-2 pathogenesis also on a regional level. In this work, we aimed …

… We report here a dysregulated immune system in a cohort of 452 patients with laboratory-confirmed
COVID-19 in Wuhan, China. Increases in NLR and T lymphopenia—in particular, a …

… IRD probably reflect dysregulated immune responses against pre-existing infections by
opportunistic pathogens, with different immunopathological mechanisms for different pathogens. …

… KDM6B regulates several transcription factors of the innate immune response, and its
expression is increased by NF-κB in response to microbial stimuli. In MDS patients, KDM6B …