Cystic fibrosis lung disease starts in the small airways: can we treat it more effectively?

HAWM Tiddens, SH Donaldson… - Pediatric …, 2010 - Wiley Online Library
… in early childhood following clinical diagnosis of cystic fibrosis. … early indicator of lung disease
in children with cystic fibrosis. … Early detection of cystic fibrosis lung disease: multiplebreath …

Newborn screening for cystic fibrosis

C Castellani, J Massie, M Sontag… - The Lancet Respiratory …, 2016 - thelancet.com
… Since the late 1970s when the potential of the immunoreactive trypsinogen assay for early
identification of infants with cystic fibrosis was first recognised, the performance of newborn …

Time to get serious about the detection and monitoring of early lung disease in cystic fibrosis

KJ Bayfield, TA Douglas, T Rosenow, JC Davies… - Thorax, 2021 - thorax.bmj.com
… techniques in early lung disease, … Cystic Fibrosis Conference. The meeting entitiled ‘Shaping
imaging and functional testing for early disease detection of lung disease in Cystic Fibrosis’…

Early markers of cystic fibrosis structural lung disease: follow-up of the ACFBAL cohort

NE Wijker, S Vidmar, K Grimwood… - European …, 2020 - Eur Respiratory Soc
… Little is known about early predictors of later cystic fibrosis (CF) structural lung disease. This
study examined early predictors of progressive structural lung abnormalities in children who …

The future of cystic fibrosis care: a global perspective

SC Bell, MA Mall, H Gutierrez, M Macek… - The Lancet …, 2020 - thelancet.com
The past six decades have seen remarkable improvements in health outcomes for people
with cystic fibrosis, which was once a fatal disease of infants and young children. However, …

Acceleration of lung disease in children with cystic fibrosis after Pseudomonas aeruginosa acquisition

MR Kosorok, L Zeng, SEH West, MJ Rock… - Pediatric …, 2001 - Wiley Online Library
… have been demonstrated in the Wisconsin Cystic Fibrosis Neonatal Screening Project,12 the
… A prospective randomized trial of early diagnosis and treatments of cystic fibrosis: a unique …

Effects of diagnosis by newborn screening for cystic fibrosis on weight and length in the first year of life

DH Leung, SL Heltshe, D Borowitz, D Gelfond… - JAMA …, 2017 - jamanetwork.com
Early diagnosis of cystic fibrosis through neonatal screening prevents severe malnutrition …
Early diagnosis of cystic fibrosis through neonatal screening prevents severe malnutrition and …

Long‐term effects of birth order and age at diagnosis in cystic fibrosis: A sibling cohort study

MG Slieker, JMW Van den Berg… - Pediatric …, 2010 - Wiley Online Library
… The impact of early cystic fibrosis diagnosis on pulmonary … Early diagnosis of cystic fibrosis
through neonatal screening … The effect of early diagnosis and treatment in cystic fibrosis: a …

[HTML][HTML] Early life growth patterns persist for 12 years and impact pulmonary outcomes in cystic fibrosis

DB Sanders, Z Zhang, PM Farrell, HCJ Lai - Journal of Cystic Fibrosis, 2018 - Elsevier
… In children with cystic fibrosis (CF), recovery from growth faltering within 2 years of diagnosis
(Responders) is associated with better growth and less lung disease at age 6 years. This …

Nutritional benefits of neonatal screening for cystic fibrosis

PM Farrell, MR Kosorok, A Laxova… - … England Journal of …, 1997 - Mass Medical Soc
… We also conclude that early initiation of comprehensive nutritional therapy prevents
malnutrition in children with pancreatic insufficiency. The essential components of nutritional …