Early detection of lung disease and its association with the nutritional status, genetic background and life events in patients with cystic fibrosis

R Kraemer, C Aebi, C Casaulta Aebischer, S Gallati - Respiration, 2000 - karger.com
… cause of morbidity and death in patients with cystic fibrosis (CF), but the … in these patients
early diagnosed and prospectively … Early diagnosis of CF can best be achieved by screening of …

Infection, inflammation, and lung function decline in infants with cystic fibrosis

, … Early Surveillance Team for Cystic Fibrosis … - American journal of …, 2011 - atsjournals.org
early diagnosis, management in a specialized center, and good nutritional status. Early cystic
fibrosis (… , suggesting that early life events may have long-term consequences in CF (6, 7). …

Progress in therapies for cystic fibrosis

K De Boeck, MD Amaral - The Lancet Respiratory Medicine, 2016 - thelancet.com
cystic fibrosis. In parallel, development of modulators that target the underlying dysfunction
in the cystic fibrosis … explored, but they are still in early stages of development. In view of the …

Detection of cystic fibrosis transmembrane conductance regulator activity in early-phase clinical trials

SM Rowe, F Accurso, JP Clancy - Proceedings of the American …, 2007 - atsjournals.org
… Advances in our understanding of cystic fibrosis pathogenesis have led to strategies …
therapies, early-phase clinical trials require extension of in vivo cystic fibrosis transmembrane …

Clinical outcomes after initial pseudomonas acquisition in cystic fibrosis

ET Zemanick, J Emerson, V Thompson… - Pediatric …, 2015 - Wiley Online Library
… To evaluate clinical outcomes associated with initial isolation of Pseudomonas aeruginosa
(Pa) in a large US cystic fibrosis (CF) cohort in the current era of widespread early Pa …

Screening for cystic fibrosis: a comparative study

JE DANKERT‐ROELSE, GJ TE MEERMAN… - Acta …, 1987 - Wiley Online Library
… The purposes of this study were to evaluate the effects of early diagnosis and treatment in
… Although the results indicate that very early diagnosis and treatment have a beneficial effect

Psychosocial impact of cystic fibrosis in adolescence

M Harrop - Nursing Children and Young People, 2007 - journals.rcni.com
effects of cystic fibrosis on the adolescent/young adult: the effect on the family, the effect on
… Much of the early research on the psychosocial impact of cystic fibrosis on the adolescent …

Cystic fibrosis therapeutics: the road ahead

LR Hoffman, BW Ramsey - Chest, 2013 - Elsevier
… The current and candidate therapies discussed in this review target one or many of these
pathophysiologic steps, and therapies addressing the earliest steps would be expected to …

Implications of early inflammation and infection in cystic fibrosis: a review of new and potential interventions

PH Weller - Pediatric Pulmonology, 1997 - Wiley Online Library
… Airway infection and inflammation occur early in cystic fibrosis (CF) lung disease, suggesting
the need for early treatment. Our current approach to routine management of CF includes a …

A two-year randomized, placebo-controlled trial of dornase alfa in young patients with cystic fibrosis with mild lung function abnormalities

…, Pulmozyme Early Intervention Trial Study Group - The Journal of …, 2001 - Elsevier
… Objective: Our objective was to determine whether long-term treatment of young patients
with cystic fibrosis (CF) with dornase alfa maintains lung function and reduces respiratory tract …