Early treatment for Covid-19 with SARS-CoV-2 neutralizing antibody sotrovimab

A Gupta, Y Gonzalez-Rojas, E Juarez… - … England Journal of …, 2021 - Mass Medical Soc
SARS-CoV-2 and multiple other sarbecoviruses, including SARS-CoV-1, the virus responsible
for the SARS … , was isolated from a patient with SARS-CoV-1. We hypothesized that a …

Fluvoxamine for the early treatment of SARS-CoV-2 infection: a review of current evidence

SN Facente, AM Reiersen, EJ Lenze, DR Boulware… - Drugs, 2021 - Springer
… A leading theory is that SARS-CoV-2 replicates in an … ), caused substantial reduction in
SARS-CoV-2 replication. The … that target the S1R as early treatment for SARS-CoV-2 infection. …

[HTML][HTML] Pathophysiological basis and rationale for early outpatient treatment of SARS-CoV-2 (COVID-19) infection

PA McCullough, RJ Kelly, G Ruocco, E Lerma… - The American journal of …, 2021 - Elsevier
… pathophysiology of SARS-CoV-2 infection in determining early outpatient treatment of the …
that relate to the patient with early infection treated at home. Therapeutic approaches based …

Multifaceted highly targeted sequential multidrug treatment of early ambulatory high-risk SARS-CoV-2 infection (COVID-19)

PA McCullough, PE Alexander… - Reviews in …, 2020 - scholarlycommons.henryford.com
… , cytokine storm, and thrombosis warrants early interventions to address all components of …
out early treatment can succumb to delayed in-hospital care and death. Prompt early initiation …

Outcome of early treatment of SARSCoV‐2 infection in patients with haematological disorders

M Mikulska, D Testi, C Russo, E Balletto… - British Journal of …, 2023 - Wiley Online Library
… Prolonged shedding of SARS-CoV-2 virus is frequent in HM patients, and this study confirmed
that even in case of early treatment during the Omicron period, 12% were still SARS-CoV-…

Favipiravir and the need for early ambulatory treatment of SARS-CoV-2 infection (COVID-19)

PA McCullough - Antimicrobial Agents and Chemotherapy, 2020 - Am Soc Microbiol
… , Doi and colleagues describe successful treatment of patients with early COVID-19 with …
clear SARS-CoV-2 from nasal secretions irrespective if it was started relatively early or later …

Early treatment to prevent progression of SARS-CoV-2 infection

MS Cohen - The Lancet Respiratory Medicine, 2022 - thelancet.com
SARS-CoV-2 in patients at high risk who are unlikely to respond to a vaccine. Bebtelovimab
has EUA for early treatment … of tixagevimab–cilgavimab for treatment of early COVID-19 must …

A Comparative Analysis of SARS-CoV-2 Antivirals Characterizes 3CLpro Inhibitor PF-00835231 as a Potential New Treatment for COVID-19

M de Vries, AS Mohamed, RA Prescott… - Journal of …, 2021 - Am Soc Microbiol
… To determine whether the action of PF-00835231 is consistent with its established role as a
3CL pro inhibitor, and to delineate the timing of early SARS-CoV-2 life cycle stages in A549 +…

How does SARS-CoV-2 cause COVID-19?

NJ Matheson, PJ Lehner - Science, 2020 - science.org
… between SARS-CoV-2 … early SARS-CoV-2 infection to severe coronavirus disease 2019
(COVID-19). Understanding the cellular basis of SARS-CoV-2 infection could reveal treatments

[HTML][HTML] Pharmacological strategies to prevent SARS-CoV-2 infection and treat the early phases of COVID-19

L Scarabel, M Guardascione, M Dal Bo… - International Journal of …, 2021 - Elsevier
… An exception is remdesivir, which is currently the only drug approved by FDA for the
treatment of moderate-to-severe COVID-19. In the early phases of infection, anti-SARS-CoV-2 …