Effect of dapagliflozin on cardiovascular outcomes according to baseline kidney function and albuminuria status in patients with type 2 diabetes: a prespecified …
TA Zelniker, I Raz, O Mosenzon, JP Dwyer… - JAMA …, 2021 - jamanetwork.com
Importance Sodium-glucose cotransporter 2 inhibitors, such as dapagliflozin, promote renal
glucose excretion and reduce cardiovascular (CV) deaths and hospitalizations for heart
failure (HHF) among patients with type 2 diabetes. The relative CV efficacy and safety of
dapagliflozin according to baseline kidney function and albuminuria status are unknown.
Objective To assess the CV efficacy and safety of dapagliflozin according to baseline
estimated glomerular filtration rate (eGFR) and urinary albumin to creatinine ratio (UACR) …
glucose excretion and reduce cardiovascular (CV) deaths and hospitalizations for heart
failure (HHF) among patients with type 2 diabetes. The relative CV efficacy and safety of
dapagliflozin according to baseline kidney function and albuminuria status are unknown.
Objective To assess the CV efficacy and safety of dapagliflozin according to baseline
estimated glomerular filtration rate (eGFR) and urinary albumin to creatinine ratio (UACR) …
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