Effect of dapagliflozin on health status in patients with preserved or mildly reduced ejection fraction

MN Kosiborod, AS Bhatt, BL Claggett… - Journal of the American …, 2023 - jacc.org
… reduced and preserved EF experience especially poor health status, 3 , 18 these findings …
Third, our findings expand on the previously reported effects of dapagliflozin on health status

Effects of dapagliflozin on symptoms, function, and quality of life in patients with heart failure and reduced ejection fraction: results from the DAPA-HF trial

MN Kosiborod, PS Jhund, KF Docherty, M Diez… - Circulation, 2020 - Am Heart Assoc
… the effects of dapagliflozin on a broad range of health status … previously reported effects of
dapagliflozin on health status, as … In the DEFINE-HF trial (Dapagliflozin Effects on Biomarkers, …

Effects of dapagliflozin in patients with kidney disease, with and without heart failure

JJV McMurray, DC Wheeler, BV Stefánsson, N Jongs… - Heart Failure, 2021 - jacc.org
… (C) consistency of effect of dapagliflozin, all according to baseline heart failure status. CV
= … their condition, and these events constitute a major health care and economic burden (1-7). …

Dapagliflozin effects on biomarkers, symptoms, and functional status in patients with heart failure with reduced ejection fraction: the DEFINE-HF trial

ME Nassif, SL Windsor, F Tang, Y Khariton, M Husain… - Circulation, 2019 - Am Heart Assoc
dapagliflozin versus placebo experienced a clinically meaningful improvement in health status
(… patient reported outcomes, dapagliflozin had favorable effects on health status at the end …

Effect of dapagliflozin on worsening heart failure and cardiovascular death in patients with heart failure with and without diabetes

MC Petrie, S Verma, KF Docherty, SE Inzucchi, I Anand… - Jama, 2020 - jamanetwork.com
… The interaction between diabetes status at baseline and the effect of dapagliflozin,
compared with placebo, on each variable of interest over the duration of the trial was tested. …

Effect of dapagliflozin on health status and quality of life across the spectrum of ejection fraction: Participant‐level pooled analysis from the DAPA‐HF and DELIVER …

AS Bhatt, MN Kosiborod… - European Journal of …, 2023 - Wiley Online Library
Dapagliflozin reduces heart failure hospitalization and cardiovascular death in patients with
… We examined the effects of dapagliflozin on health status, measured by the Kansas City …

Effect of dapagliflozin on cardiovascular outcomes according to baseline kidney function and albuminuria status in patients with type 2 diabetes: a prespecified …

TA Zelniker, I Raz, O Mosenzon, JP Dwyer… - JAMA …, 2021 - jamanetwork.com
… HHF was significantly larger for dapagliflozin-treated patients who … effect of dapagliflozin
on the relative risk for CV events was consistent across kidney function and albuminuria status, …

Efficacy and safety of dapagliflozin by baseline glycemic status: a prespecified analysis from the DAPA-CKD trial

F Persson, P Rossing, P Vart, GM Chertow… - Diabetes …, 2021 - Am Diabetes Assoc
… In this prespecified analysis of the DAPA-CKD trial, we demonstrate that the effects of
dapagliflozin on kidney failure, heart failure, and mortality outcomes were consistent regardless of …

Effect of dapagliflozin on clinical outcomes in patients with chronic kidney disease, with and without cardiovascular disease

JJV McMurray, DC Wheeler, BV Stefánsson, N Jongs… - Circulation, 2021 - Am Heart Assoc
… Here, we report the effects of dapagliflozin on the prespecified kidney and cardiovascular …
to baseline cardiovascular disease status, renal risk did not. Dapagliflozin was similarly …

Effect of dapagliflozin on anaemia in DAPA‐HF

KF Docherty, JP Curtain, IS Anand… - European journal of …, 2021 - Wiley Online Library
… We also analysed the effect of dapagliflozin on outcomes, according to anaemia status at …
A score of ≥75 is considered to reflect satisfactory health status; LVEF, left ventricular ejection …