Effect of dapagliflozin according to baseline systolic blood pressure in the Dapagliflozin and Prevention of Adverse Outcomes in Heart Failure trial (DAPA-HF)

M Serenelli, M Böhm, SE Inzucchi, L Køber… - European heart …, 2020 - academic.oup.com
… ), the effect of treatment according to baseline DBP and the effect of treatment … heart
failure aetiology. As reported in another recent study, 8 we also analysed outcomes in patients

Effects of dapagliflozin in patients with kidney disease, with and without heart failure

…, DAPA-CKD Trial Committees and Investigators - Heart Failure, 2021 - jacc.org
effects of dapagliflozin in chronic kidney disease (CKD) patients, with and without heart failure
… We calculated HRs (95% CIs) for the effect of dapagliflozin 10 mg, compared with placebo…

Effect of dapagliflozin on heart failure and mortality in type 2 diabetes mellitus

ET Kato, MG Silverman, O Mosenzon, TA Zelniker… - Circulation, 2019 - Am Heart Assoc
cardiovascular outcome trial to evaluate patients with type 2 diabetes mellitus stratified by
EF, we found that dapagliflozin reduced HHF in patients with … study shows that dapagliflozin

Effects of dapagliflozin on symptoms, function, and quality of life in patients with heart failure and reduced ejection fraction: results from the DAPA-HF trial

MN Kosiborod, PS Jhund, KF Docherty, M Diez… - Circulation, 2020 - Am Heart Assoc
… in patients with heart failure and reduced ejection fraction. In this analysis, we examine
the effects of dapagliflozin on a … , using the Kansas City Cardiomyopathy Questionnaire (KCCQ). …

[HTML][HTML] Dapagliflozin in patients with heart failure and reduced ejection fraction

JJV McMurray, SD Solomon, SE Inzucchi… - … England Journal of …, 2019 - Mass Medical Soc
… regarding the effects of SGLT2 inhibitors in patients with established hearttrial, we randomly
assigned 4744 patients with New York Heart Association class II, III, or IV heart failure and …

Effect of dapagliflozin on worsening heart failure and cardiovascular death in patients with heart failure with and without diabetes

MC Petrie, S Verma, KF Docherty, SE Inzucchi, I Anand… - Jama, 2020 - jamanetwork.com
… The aim of the study was to enroll patients with heart failure and reduced ejection fraction.
Individuals with type 2 diabetes were to continue to receive their glucose-lowering treatments, …

Effects of dapagliflozin in DAPA-HF according to background heart failure therapy

KF Docherty, PS Jhund, SE Inzucchi… - European heart …, 2020 - academic.oup.com
… In the DAPA-HF trial, the SGLT2 inhibitor dapagliflozin reduced the risk of worsening
heart failure (HF) and death in patients with HF and reduced ejection fraction. We examined …

The SGLT2 inhibitor dapagliflozin in heart failure with preserved ejection fraction: a multicenter randomized trial

ME Nassif, SL Windsor, BA Borlaug, DW Kitzman… - Nature medicine, 2021 - nature.com
… Consistent with previous data from comparably sized trials, dapagliflozin treatment had no
significant effect on natriuretic peptides 10 . Although natriuretic peptide levels are predictive …

Dapagliflozin effects on biomarkers, symptoms, and functional status in patients with heart failure with reduced ejection fraction: the DEFINE-HF trial

ME Nassif, SL Windsor, F Tang, Y Khariton, M Husain… - Circulation, 2019 - Am Heart Assoc
… and reduced ejection fraction, use of dapagliflozin over 12 weeks did not affecteffects of
dapagliflozin in heart failure with reduced ejection fraction may potentially extend to patients

[HTML][HTML] Dapagliflozin in heart failure with mildly reduced or preserved ejection fraction

SD Solomon, JJV McMurray, B Claggett… - … England Journal of …, 2022 - Mass Medical Soc
patients with heart failure and a left ventricular ejection fraction of more than 40% to receive
dapagliflozin (… The primary outcome was a composite of worsening heart failure (which was …