… Using V2-specific antibodies previously isolated from donor CAP256, we showed that the
IgG3 constant region improved both Fc effector function and neutralization potency. This effect …

… isotype on Fc effector function and neutralization activity of 15 … Finally we demonstrate that
neutralization potency of these … Fc effector function but also show enhanced neutralization …

… neutralizing’ or ‘extra-neutralizing’ encourage the perception that only antibodies that do not
neutralize can mediate potent Fc effector functions… by many neutralizing antibodies can be …

… if or when non-neutralizing functions of antibodies are capable … of non-neutralizing antibody
effector functions in protection … dependent on the inherent neutralization potency and titre of …

… However, the role of antibody effector function, relative neutralization potency, and combinations
in protection have not been examined to date in part because performing experiments …

… -neutralizing antibodies is controversial. Here, I review the literature suggesting a role for
Fc-mediated effector by non-neutralizing … of Fc-mediated effector function by nonneutralizing …

… potent bnAb had the same dependence on effector function for protection as a first-generation,
less potent … Another hypothesis was whether a contribution of effector function could be …

… potency had no relationship with neutralization potency or breadth for any epitope cluster.
Thus, Fc-mediated effector function and neutralization … , neutralization, and effector function. …

… mediated effector function plays a role in protection against infection by broadly neutralizing
… Vpu might further increase the potency of these non-neutralizing antibodies and should be …

… a potent SARS-CoV-2 neutralizing antibody, isolated from a convalescent patient.
Antibody-mediated neutralization … SC31 exhibited potent anti-SARS-CoV-2 activities in multiple …