… The recombinant virus, mouse-adapted SARS-CoV-2 (SARS-CoV-2 … effectorfunction, and antibody combinations on protection from SARS-CoV-2 MA infection in mice and SARS-CoV…
G Beaudoin-Bussières, A Finzi - Trends in Microbiology, 2024 - cell.com
… effectorfunctions. Here, we review these assays and what is known regarding anti-SARS-CoV-2 Fc-effector … current state of knowledge regarding anti-SARS-CoV-2 Fc-effectorfunctions. …
… (mAbs) in SARS-CoV-2-infected animals. Whereas Fc effectorfunctions are dispensable when … When given after infection, intact mAbs reduce SARS-CoV-2 burden and lung disease in …
… To begin to evaluate the contribution of Fc effectorfunctions to antibody protection against SARS-CoV-2 infection, we profiled vaccine-induced antibodies from sera pooled from …
… While FcR binding is required to initiate Fc-effectorfunction, we next sought to profile the … vaccine platforms, focused on the WT and Omicron SARS-CoV-2 Spike antigens. Although the …
R Gao, C Feng, Z Sheng, F Li… - Journal of Medical …, 2024 - Wiley Online Library
… Fc-effectorfunctions play a crucial role in combating SARS-CoV-2 … of Fc-effectorfunctions in broadly disarming SARS-CoV-2 … antibody function to develop an effective SARS-CoV-2 …
A Tauzin, M Nayrac, M Benlarbi, SY Gong, R Gasser… - Cell host & …, 2021 - cell.com
… SARS-CoV-2 naive individuals but strong anti-receptor binding domain and spike antibodies with Fc-mediated effectorfunctions … of Fc-mediated effectorfunctions and T cell responses …
CEZ Chan, SGK Seah, DH Chye, S Massey, M Torres… - PLoS …, 2021 - journals.plos.org
Although SARS-CoV-2-neutralizing antibodies are promising therapeutics against COVID-19, little is known about their mechanism(s) of action or effective dosing windows. We report …
P Kaplonek, S Fischinger, D Cizmeci, YC Bartsch… - Immunity, 2022 - cell.com
… Thus, we aimed to define whether Fc effectorfunctions were equally disrupted across VOCs. Given the ability of VOCs to re-infect previously naturally immune individuals ( …