[HTML][HTML] Safety and immunogenicity of an AMA1 malaria vaccine in Malian children: results of a phase 1 randomized controlled trial

MA Thera, OK Doumbo, D Coulibaly, MB Laurens… - PloS one, 2010 - journals.plos.org
… AS02 A vaccine had a good safety profile, was well-tolerated, and induced high and … in
malaria-exposed children. This malaria vaccine is being evaluated in a Phase 2 efficacy trial in …

[HTML][HTML] Safety, infectivity and immunogenicity of a genetically attenuated blood-stage malaria vaccine

R Webster, S Sekuloski, A Odedra, S Woolley… - BMC medicine, 2021 - Springer
… to malaria vaccine development. We aimed to develop a genetically attenuated blood-stage
vaccine and test its safety, … -stage GAP malaria vaccine and characterize its safety, infectivity, …

[HTML][HTML] Status of vaccine research and development of vaccines for malaria

AJ Birkett - Vaccine, 2016 - Elsevier
… goal for a modestly efficacious malaria vaccine yielding … vaccine candidate now under
regulatory and policy review. There are three general approaches to developing malaria vaccines, …

[HTML][HTML] Safety of the Malaria Vaccine Candidate, RTS,S/AS01E in 5 to 17 Month Old Kenyan and Tanzanian Children

J Lusingu, A Olotu, A Leach, M Lievens, J Vekemans… - PLoS …, 2010 - journals.plos.org
… The malaria vaccine candidate, RTS,S/AS01 E , showed promising protective efficacy in a …
Here we report on the vaccine's safety and tolerability. The experimental design was a Phase …

Safety of the RTS, S/AS02D candidate malaria vaccine in infants living in a highly endemic area of Mozambique: a double blind randomised controlled phase I/IIb trial

JJ Aponte, P Aide, M Renom, I Mandomando, Q Bassat… - The Lancet, 2007 - thelancet.com
… We aimed to assess the safety, immunogenicity, and initial efficacy of the malaria vaccine
In this paper, we report the results of the first evaluation of safety, immunogenicity, and efficacy

The first field trials of the chemically synthesized malaria vaccine SPf66: safety, immunogenicity and protectivity

R Amador, A Moreno, V Valero, L Murillo, AL Mora… - Vaccine, 1992 - Elsevier
… This paper reports the results of the first field study performed to assess the safety,
immunogenicity and protectivity of the synthetic malaria vaccine SPf66 directed against the asexual …

Safety and immunogenicty of RTS, S/AS02A candidate malaria vaccine in Gambian children

KA Bojang, F Olodude, M Pinder, O Ofori-Anyinam… - Vaccine, 2005 - Elsevier
malaria occurs in young children [5]. In order to ultimately evaluate the safety and efficacy of
the RTS,S/AS02A candidate vaccine … escalation and dose escalation safety trials in children. …

Malaria vaccine R&D in the Decade of Vaccines: breakthroughs, challenges and opportunities

AJ Birkett, VS Moorthy, C Loucq, CE Chitnis… - Vaccine, 2013 - Elsevier
… interventions, including vaccines to prevent … malaria vaccine development efforts, with
particular emphasis on the impact of the possible availability of a first generation malaria vaccine

Malaria vaccine developments

VS Moorthy, MF Good, AVS Hill - The lancet, 2004 - thelancet.com
… for other diseases are being evaluated first in malaria. We describe progress in malaria
vaccine development in the past 5 years: reasons for cautious optimism, the type of vaccine that …

The development of the RTS, S malaria vaccine candidate: challenges and lessons

WR Ballou - Parasite immunology, 2009 - Wiley Online Library
… a consultation with the malaria vaccine community and leading statisticians that helped
reassure that the methodologies that we have used in our malaria vaccine field trials and the …