R Webster, S Sekuloski, A Odedra, S Woolley… - BMC medicine, 2021 - Springer
… to malariavaccine development. We aimed to develop a genetically attenuated blood-stage vaccine and test its safety, … -stage GAP malariavaccine and characterize its safety, infectivity, …
… goal for a modestly efficaciousmalariavaccine yielding … vaccine candidate now under regulatory and policy review. There are three general approaches to developing malariavaccines, …
… The malariavaccine candidate, RTS,S/AS01 E , showed promising protective efficacy in a … Here we report on the vaccine'ssafety and tolerability. The experimental design was a Phase …
JJ Aponte, P Aide, M Renom, I Mandomando, Q Bassat… - The Lancet, 2007 - thelancet.com
… We aimed to assess the safety, immunogenicity, and initial efficacy of the malariavaccine … In this paper, we report the results of the first evaluation of safety, immunogenicity, and efficacy …
… This paper reports the results of the first field study performed to assess the safety, immunogenicity and protectivity of the synthetic malariavaccine SPf66 directed against the asexual …
KA Bojang, F Olodude, M Pinder, O Ofori-Anyinam… - Vaccine, 2005 - Elsevier
… malaria occurs in young children [5]. In order to ultimately evaluate the safety and efficacy of the RTS,S/AS02A candidate vaccine … escalation and dose escalation safety trials in children. …
AJ Birkett, VS Moorthy, C Loucq, CE Chitnis… - Vaccine, 2013 - Elsevier
… interventions, including vaccines to prevent … malariavaccine development efforts, with particular emphasis on the impact of the possible availability of a first generation malariavaccine …
… for other diseases are being evaluated first in malaria. We describe progress in malaria vaccine development in the past 5 years: reasons for cautious optimism, the type of vaccine that …
… a consultation with the malariavaccine community and leading statisticians that helped reassure that the methodologies that we have used in our malariavaccine field trials and the …