Malaria vaccine trials in pregnant women: an imperative without precedent

SA Healy, M Fried, T Richie, K Bok, M Little, A August… - Vaccine, 2019 - Elsevier
malaria vaccines that offer direct benefits to pregnant women. Initial safety and immunogenicity
studies of malaria vaccines … Subsequently, efficacy trials involving pregnant women will …

Efficacy of RTS, S/AS02 malaria vaccine against Plasmodium falciparum infection in semi-immune adult men in The Gambia: a randomised trial

KA Bojang, PJM Milligan, M Pinder, L Vigneron… - The Lancet, 2001 - thelancet.com
… We thank the volunteers who participated in this study; the malaria field and laboratory
staff; the Local Safety Monitor (Dr Tumani Corrah); the Data Safety Monitoring Committee (Chair, …

[HTML][HTML] Safety evaluation of SPf66 malaria vaccine in Brazil

LM Urdaneta, A Prata, CJ Struchiner… - Revista da Sociedade …, 1996 - SciELO Brasil
… to the subcutaneous application of SPf66 malaria vaccine and placebo are reported for
each dose of application in the participants of the vaccine efficacy trial in Brazil. Side effects …

Malaria vaccine clinical trials: what's on the horizon

A Moreno, C Joyner - Current opinion in immunology, 2015 - Elsevier
… vivax vaccine research requires more momentum and additional … vaccine candidates. In
this review, recently completed and ongoing malaria vaccine clinical trials as well as vaccine

[HTML][HTML] Seasonal malaria vaccination with or without seasonal malaria chemoprevention

D Chandramohan, I Zongo, I Sagara… - … England Journal of …, 2021 - Mass Medical Soc
… seasonal vaccination with the RTS,S/AS01 E malaria vaccine after priming was noninferior to
… in preventing clinical malaria and whether a combination of the RTS,S/AS01 E vaccine and …

Mosquirix (RTS, S): a novel vaccine for the prevention of Plasmodium falciparum malaria

KJ Wilby, TTY Lau, SE Gilchrist… - Annals of …, 2012 - journals.sagepub.com
… To summarize and evaluate the literature for Mosquirix (RTS,S) and provide insight into
the therapeutic and economic controversies of this novel malaria vaccine candidate. …

[HTML][HTML] Safety and immunogenicity of an AMA-1 malaria vaccine in Malian adults: results of a phase 1 randomized controlled trial

MA Thera, OK Doumbo, D Coulibaly, DA Diallo… - PloS one, 2008 - journals.plos.org
malaria remains a major global killer, especially of infants and children, and a serious
threat to travelers. A safe and effective malaria vaccine … health and economies of malaria-endemic …

Efficacy of RTS, S/AS01E malaria vaccine and exploratory analysis on anti-circumsporozoite antibody titres and protection in children aged 5–17 months in Kenya and …

A Olotu, J Lusingu, A Leach, M Lievens… - The Lancet infectious …, 2011 - thelancet.com
… the lead candidate malaria vaccine. We recently showed efficacy against clinical falciparum
malaria in 5… We aimed to assess the efficacy of RTS,S/AS01E during 15 months of follow-up. …

[HTML][HTML] Efficacy of RTS, S malaria vaccines: individual-participant pooled analysis of phase 2 data

P Bejon, MT White, A Olotu, K Bojang… - The Lancet infectious …, 2013 - thelancet.com
Efficacy of RTS,S/AS02 malaria vaccine against Plasmodium falciparum infection in semi-…
Safety of the RTS,S/AS02D candidate malaria vaccine in infants living in a highly endemic …

Randomized double-blind controlled Phase I/IIa trial to assess the efficacy of malaria vaccine PfCS102 to protect against challenge with P. falciparum

B Genton, V D'Acremont, F Lurati-Ruiz, D Verhage… - Vaccine, 2010 - Elsevier
… controlled trial was to test the efficacy of the sporozoite-based malaria vaccine PfCS 282–383
(… 8/8 vaccinees and 6/6 controls challenged developed malaria parasitaemia. The duration …