Bivalirudin Versus Heparin Monotherapy in Patients with ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention: A …

B Sun, RR Chen - Cardiovascular Drugs and Therapy, 2024 - Springer
… than heparin monotherapy for STEMI patients undergoing primary PCI [… safety and
effectiveness of bivalirudin plus post-PCI infusion in comparison to heparin alone for STEMI patients

Unfractionated heparin versus bivalirudin in primary percutaneous coronary intervention (HEAT-PPCI): an open-label, single centre, randomised controlled trial

A Shahzad, I Kemp, C Mars, K Wilson, C Roome… - The Lancet, 2014 - thelancet.com
… The relative safety and efficacy of heparin and bivalirudin needed to be assessed in a
study design representing modern PPCI practice. Our trial, How Effective are Antithrombotic …

Validation of long-term benefits of bivalirudin versus unfractionated heparin in routine clinical practice after percutaneous coronary intervention

VD Vidi, ME Matheny, V Agarwal, N Arora… - The American journal of …, 2010 - Elsevier
… (66%) received UFH and 1,139 (34%) received bivalirudin. … In a propensity-score matched
analysis, bivalirudin-based … a real-world cohort of patients undergoing PCI, bivalirudin-based …

Bivalirudin, a bivalent, thrombin specific anticoagulant as an alternative to heparin in interventional procedures

DP Chew - Hämostaseologie, 2002 - thieme-connect.com
bivalirudin from hirudin is the reversibility of the bivalirudin:… in 88% of patients and 24% of
bivalirudintreated patients also … Patients treated with bivalirudin had a lower incidence of death, …

Bivalent direct thrombin inhibitors: hirudin and bivalirudin

TE Warkentin - Best Practice & Research Clinical Haematology, 2004 - Elsevier
… , have been overcome through development of the hirudin analogue, bivalirudin.
Compared with hirudin derivatives, bivalirudin exhibits a shorter half-life (25 vs 80 minutes), …

Reduced-dose without the post-procedure infusion of bivalirudin in patients with acute coronary syndrome undergoing elective percutaneous coronary intervention

Q Wang, T Zhou, L Yang, J Li, Q Zhang, X Wang - 2023 - researchsquare.com
… To evaluate the efficacy of intraoperative application of 80% bivalirudin, patients with ACS
were included in this study. In the BRIGHT study (24), the recommended dose infusion was …

Incidence and prognostic value of bleeding after percutaneous coronary intervention in patients older than 75 years of age

G Ndrepepa, FJ Neumann, S Schulz… - Catheterization and …, 2014 - Wiley Online Library
… use of bivalirudin as post-PCI anticoagulant strategy was associated with a decrease in the
bleeding risk, and thus, it may be an efficient bleeding avoidance strategy in elderly patients

Primary angioplasty in patients older than 75 years. Profile of patients and procedures, outcomes, and predictors of prognosis in the ESTROFA IM+ 75 Registry

JM de la Torre Hernández, S Brugaletta… - Revista Española de …, 2017 - Elsevier
… The proportion of elderly patients undergoing primary … Notably, bivalirudin was not a
predictor of stent thrombosis or … recommendations for these patients, bivalirudin use would a …

Novel approaches for preventing or limiting events (Naples) III trial: randomized comparison of bivalirudin versus unfractionated heparin in patients at increased risk of …

C Briguori, G Visconti, A Focaccio, M Donahue… - JACC: Cardiovascular …, 2015 - jacc.org
… This study sought to assess the safety and the efficacy of bivalirudin compared with unfractionated
heparin (UFH) alone in the subset of patients at increased risk of bleeding undergoing …

Population pharmacokinetics and pharmacodynamics of bivalirudin in young healthy Chinese volunteers

D Zhang, K Wang, X Zhao, Y Li, Q Zheng… - Acta Pharmacologica …, 2012 - nature.com
… the bivalirudin anticoagulant effect from the placebo effect. The bivalirudin treatment group
… The selection of doses was based on the instructions for bivalirudin use marketed in the …