[HTML][HTML] How does SARS-CoV-2 targets the elderly patients? A review on potential mechanisms increasing disease severity

A Smorenberg, EJG Peters, PLA van Daele… - European Journal of …, 2021 - Elsevier
… In this narrative review we address the issue: Why do elderly patients have a higher risk of …
presentations of SARS-CoV-2 are frequent and may delay diagnosis in elderly patients. In the …

Cytokine response in SARS-CoV-2 infection in the elderly

S Sherwani, MWA Khan - Journal of Inflammation Research, 2020 - Taylor & Francis
… such as seen in SARS, MERS and SARS-CoV-2 infected patients. A fine balance of … Elderly
patients with SARS also exhibited a poor prognosis with mortality rates of 50% in patients

Caution should be exercised for the detection of SARSCoV‐2, especially in the elderly

Y Yuan, N Wang, X Ou - Journal of medical virology, 2020 - Wiley Online Library
… for the changes of results of SARS-CoV-2 RNA should attract attention. Most patients were
elderly, with a low … GNRI may be useful in identifying high risk elderly patients with COVID-19. …

SARS-CoV-2 infection represents a high risk for the elderly: analysis of pathogenesis

A Pedreañez, J Mosquera-Sulbaran, N Muñoz - Archives of Virology, 2021 - Springer
… Since it is difficult to predict the progression of SARS-CoV-2 infection, it is reasonable …
SARS-CoV-2 infection may be important for preventing severe disease in elderly patients, patients

[HTML][HTML] Elderly patient care: a new reality of the SARS-CoV-2 pandemic

B Jankowska-Polańska, K Sarzyńska, A Pytel… - Aging and …, 2021 - ncbi.nlm.nih.gov
… infection risk among elderly patients, but old age is reported as an independent risk factor
both for death from SARS-CoV-2 and for a severe course of infection. Patients aged over 60 …

Outcomes of elderly patients hospitalized with the SARS-CoV-2 omicron B. 1.1. 529 variant: A systematic review

RM Fericean, C Oancea, AR Reddyreddy… - International Journal of …, 2023 - mdpi.com
… acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) … older age patients (>65) that are
hospitalized with the SARS-CoV-… The inclusion criteria comprised (1) a population of patients

A systematic review of lung autopsy findings in elderly patients after SARS-CoV-2 infection

S Septimiu-Radu, T Gadela, D Gabriela… - Journal of clinical …, 2023 - mdpi.com
… A total of 478 autopsies were analyzed in the current systematic review on a total of 478
unique patients who died after acute severe SARS-CoV-2 infection confirmed through an RT-…

[HTML][HTML] Age-induced NLRP3 inflammasome over-activation increases lethality of SARS-CoV-2 pneumonia in elderly patients

PC Lara, D Macías-Verde, J Burgos-Burgos - Aging and disease, 2020 - ncbi.nlm.nih.gov
… and fibrosis in SARS-CoV and SARS-CoV-2 infections. Increased … This NLRP3 over-activated
status in elderly individuals, is … lethality observed in elderly patients infected by COVID-19. …

Pattern of SARS-CoV-2 infection among dependant elderly residents living in long-term care facilities in Marseille, France, March–June 2020

TDA Ly, D Zanini, V Laforge, S Arlotto, S Gentile… - International journal of …, 2020 - Elsevier
SARS-CoV-2 carriage among elderly residents and staff members working in 24 LTCFs in
Marseille, France. It also aimed to estimate the fatality among elderly … among elderly patients

Susceptibility of the elderly to SARS-CoV-2 infection: ACE-2 overexpression, shedding, and antibody-dependent enhancement (ADE)

JPS Peron, H Nakaya - Clinics, 2020 - SciELO Brasil
… to circulating coronaviruses with low neutralizing capacity to SARS-CoV-2 may greatly
contribute to the increased susceptibility of the elderly patients to COVID-19. To determine …