An elegant defense: how neutrophils shape the immune response

O Soehnlein - Trends in immunology, 2009 - cell.com
… A key function of the immune system is to prevent the body's hostile takeover by microbes.
Central to this host defense is the recognition and elimination of microbes. Neutrophils have …

Evolution of the innate immune system: the worm perspective

H Schulenburg, C Léopold Kurz… - Immunological …, 2004 - Wiley Online Library
… on the immune system in a strict sense, ie the physiological defense system, whereas other
facets of defense … elegans immunity was inferred from an elegant genetic screen (43). The F2 …

Phagocytosis: elegant complexity

LM Stuart, RAB Ezekowitz - Immunity, 2005 - cell.com
Phagocytosis requires receptor-mediated recognition of particles, usually in the guise of
infectious agents and apoptotic cells. Phagosomes fuse with lysosomes to generate …

Evolution of immune systems from self/not self to danger to artificial immune systems (AIS)

EL Cooper - Physics of life reviews, 2010 - Elsevier
… There will be a focus on concepts that propelled the immune system into prominent … universal
innate immune system of ubiquitous and plentiful invertebrates as an essential system for …

Fifty shades of immune defense

MF Criscitiello, P de Figueiredo - PLoS pathogens, 2013 - journals.plos.org
… transferred to naïve congenic siblings have elegantly demonstrated that a persistent population
… Hence, the elegant immunogenetic trickery of the RAG recombinase upon IgSF loci that …

The evolution of immune mechanisms

N Danilova - Journal of Experimental Zoology Part B: Molecular …, 2006 - Wiley Online Library
… in a layered structure of the immune system. The immune system is not one system but
rather a sophisticated network of various defensive mechanisms operating on different levels, …

G protein-coupled receptors: The choreographers of innate immunity in Caenorhabditis elegans

SR Venkatesh, V Singh - PLoS pathogens, 2021 - journals.plos.org
… In this review, we examined a number of elegant studies in C. elegans demonstrating
immune-modulatory roles of neuronal and nonneuronal GPCRs. Notably, some studies in …

Beyond host defense: emerging functions of the immune system in regulating complex tissue physiology

LC Rankin, D Artis - Cell, 2018 - cell.com
… The birth of elegant imaging techniques and mouse models together with multi-parameter …
the role of neurons in the regulation of the immune system, and, thus, this warrants revisiting ( …

Overview of the immune response

DD Chaplin - Journal of allergy and clinical immunology, 2010 - Elsevier
… arm of the immune system is to recognize host cells that are infected by viruses, intracellular
bacteria, or other intracellular parasites, T cells have evolved an elegant mechanism that …

Chemokines in Innate and Adaptive Host Defense: Basic Chemokinese Grammar for Immune Cells

A Rot, UH Von Andrian - Annu. Rev. Immunol., 2004 - annualreviews.org
… a sophisticated communication system used by all our cell types, including immune cells. …
Critical determinants of the in vivo activities of chemokines in the immune system include their …