GJ Nuovo, C Magro, T Shaffer, H Awad, D Suster… - Annals of diagnostic …, 2021 - Elsevier
… induced by complement and cytokine mediated endothelial damage triggered by circulating … of the spikeprotein alone (without infectious virus) on human endothelialcells in culture and …
S Raghavan, DB Kenchappa, MD Leo - Frontiers in cardiovascular …, 2021 - frontiersin.org
… -2 spikeprotein binds to the ACE2 receptor in endothelialcells … of critical proteins that maintain endothelial barrier function … cells and in healthy mouse cerebral arteries, spikeprotein …
BM Rotoli, A Barilli, R Visigalli, F Ferrari, V Dall'Asta - Biomedicines, 2021 - mdpi.com
… of mice, thus affecting the endothelial barrier function [41]. Taken … the endothelium. Interestingly, the activation we observed upon the exposure of endothelialcells to the spikeprotein …
AC Montezano, LL Camargo, S Mary, KB Neves… - Scientific Reports, 2023 - nature.com
… S1 protein induces endothelial inflammation and cell damage independently of viral infection To study the global effect of SARS-CoV-2 spikeprotein on endothelialcellprotein …
JP Robles, M Zamora, E Adan-Castro… - Journal of Biological …, 2022 - ASBMB
… Peripheral blood leukocytes were incubated for 1 h with human umbilical vein endothelialcells (HUVECs) pretreated for 16 h with spike, the receptor-binding domain of …
L Schimmel, KY Chew, CJ Stocks… - Clinical & …, 2021 - Wiley Online Library
… SARS-CoV-2 nucleocapsid protein in SARS-CoV-2-treated endothelialcells by … 2 spike protein can induce the breakdown of the vascular barrier in brain microvascular endothelialcells. …
… levels of spikeprotein in any of the endothelialcells studied … endothelialcell found to be positive for spikeprotein. Together these data suggest that only coronary artery endothelialcells …
… Our results show that the SARS-CoV-2 spikeprotein is … smooth muscle and endothelialcells, which suggests that cell growth … and endothelialcells revealed that the SARS-CoV-2 spike …
Y Lei, J Zhang, CR Schiavon, M He, L Chen… - Circulation …, 2021 - Am Heart Assoc
… SARS-CoV-1 S protein promotes lung injury by decreasing the … that S protein alone can damage vascular endothelialcells (… a pseudovirus expressing S protein (Pseu-Spike) to Syrian …