… This review provides a comprehensive overview of the mechanisms underlying cytokine
storm, summarizes its pathophysiology and improves understanding of cytokine storm …

… This review enlightened the implications and risk factor of hypercytokinemia/cytokine storm
for COVID-19 patients, with special emphasis on potential therapeutic strategies used to …

“Cytokine storm syndrome” is a diverse set of … cytokine storm are heterogeneous and derive
from rheumatologic, oncologic, and infectious origins. The first member of the cytokine storm …

… inflammation, which is called the cytokine storm. Cytokine storm is also argued to greatly
contribute to the COVID-19 disease [5-7]. The cytokine storm caused by the virus is the result of …

… respiratory syndrome coronavirus 2” (SARSCoV-2) is yet to be enlightened further. Inflammatory
process along with the damage of the host’s immune system plays a pivotal role in all …

… ” refers to a scenario in which several cytokines released are harmful to the host [9, 38]. … of
an excessive cytokine storm [2]. It is worth noting that the production of numerous cytokines is …

… The hallmark of COVID-19 pathogenesis is the cytokine storm with elevated levels of
interleukin-6 (IL-6), IL-1β, tumor necrosis factor-alpha (TNF-α), chemokine (CC-motif) ligand 2 (…

The last 50 years have been marked by increased understanding of the underpinnings of
sepsis, its myriad manifestations and optimal approaches to therapy. The 50-year timeline that …

… Alleviating overproduction of reactive oxygen species and cytokine storm in COVID-19 is …
, cytokine storm, hyperinflammation, and diminish the risk of organ failure. Direct antiviral roles …

… and the ability to contribute to the cytokine storm characteristic of COVID-19 (44). Aging is …
increase inflammatory responses leading to the cytokine storm for which the disease is …