The clinical use of angiotensin-converting enzyme inhibitors

J Wong, RA Patel, PR Kowey - Progress in cardiovascular diseases, 2004 - Elsevier
… (RAAS), ACE inhibitors and ARB clinicalclinical trial data. It is envisioned that an updated
and detailed understanding of ACE inhibitors and ARBs will facilitate their successful use in …

Long-term use of angiotensin-converting enzyme inhibitors to modify endothelial dysfunction: a review of clinical investigations

GBJ Mancini - Clinical and investigative medicine, 2000 - search.proquest.com
… angiotensin-converting enzyme (ACE) inhibitors. The purpose of this paper is to review clinical
studies assessing the effect of long-term, oral ACE inhibition on endothelial dysfunction in …

[PDF][PDF] Effectiveness of enzyme inhibitors in biomedicine and pharmacotherapy

A Ouertani, M Neifar, R Ouertani… - Adv. Tissue Eng …, 2019 - researchgate.net
… The impact of enzyme inhibitorsenzyme inhibitors are currently marketed and double than
those are under development. Such inhibitors exhibit their specific action in enzyme inhibition

Targeting enzyme inhibitors in drug discovery

RA Copeland, MR Harpel… - Expert opinion on …, 2007 - Taylor & Francis
enzyme molecules as well. Within the collection of enzyme inhibitors that are presently in
clinical use as drugs, one finds representatives of all of these inhibition modalities, as well as …

Clinical use of an orally acting converting enzyme inhibitor: captopril.

HR Brunner, H Gavras, B Waeber, SC Textor… - …, 1980 - Am Heart Assoc
SUMMARY An orally Retire inhibitor of the angtotensin conrerting enzyme, SQ 14,225 or
captopril, was administered to 14 normal rolnnteers to evaluate its efficacy in inhibiting the …

Angiotensin-converting enzyme inhibitors in hypertension: to use or not to use?

FH Messerli, S Bangalore, C Bavishi… - Journal of the American …, 2018 - jacc.org
… Angiotensin receptor blockers showed the highest reduction in systolic and diastolic blood
pressure compared with angiotensin-converting enzyme inhibitors and direct renin inhibitors. …

[HTML][HTML] Angiotensin‐converting enzyme inhibitors

JL Izzo Jr, MR Weir - The Journal of Clinical Hypertension, 2011 - ncbi.nlm.nih.gov
… The intent of this review is to integrate relevant human basic science and outcome data in
order to promote a sophisticated yet practical approach to clinical use of ACE inhibitors. In …

Clinical pharmacokinetics of the angiotensin converting enzyme inhibitors: a review

SH Kubo, RJ Cody - Clinical pharmacokinetics, 1985 - Springer
… The angiotensin converting enzyme inhibitors are an important therapeutic advance in the
… Captopril was the first angiotensin converting enzyme inhibitor approved for use in patients …

A counterintuitive approach to treat enzyme deficiencies: use of enzyme inhibitors for restoring mutant enzyme activity

JQ Fan - 2008 - degruyter.com
… normal level, whereas residual enzyme activity can be detected … enzyme inhibitors can
effectively increase mutant enzyme … sub-inhibitory concentrations, and we proposed that enzyme

Enzyme inhibitors in medicine

CSJ Walpole, R Wrigglesworth - Natural Product Reports, 1989 - pubs.rsc.org
… the description of enzyme inhibitors which have found use in clinical practice and also the …
a catalogue of enzymes, diseases, enzyme inhibitors, and their attendant clinical benefits. This …