Esophageal distensibility as a measure of disease severity in patients with eosinophilic esophagitis

F Nicodème, I Hirano, J Chen, K Robinson, Z Lin… - Clinical …, 2013 - Elsevier
… subsequent requirement for esophageal dilation during follow-up evaluation. In addition, we
sought to compare esophageal distensibility with the severity of mucosal eosinophilia as an …

Influence of age and eosinophilic esophagitis on esophageal distensibility in a pediatric cohort

C Menard-Katcher, AJ Benitez, Z Pan… - Official journal of the …, 2017 - journals.lww.com
… Using the novel endoscopic tool, FLIP, we show for the first time that pediatric esophageal
distensibility is significantly decreased in children with active EoE compared with non-EoE …

Improvement in esophageal distensibility in response to medical and diet therapy in eosinophilic esophagitis

DA Carlson, I Hirano, A Zalewski… - Clinical and …, 2017 - journals.lww.com
… We aimed to evaluate the effect of medical and diet therapies on esophageal distensibility
… in esophageal distensibility with clinical outcomes in eosinophilic esophagitis (EoE). …

Severity of endoscopically identified esophageal rings correlates with reduced esophageal distensibility in eosinophilic esophagitis

JW Chen, JE Pandolfino, Z Lin, JD Ciolino… - …, 2016 - thieme-connect.com
… In this study, FLIP quantification of esophageal distensibility was not significantly associated
with the degree of mucosal eosinophilia, again indicative of the dissociation between the …

Esophageal distensibility defines fibrostenotic severity in pediatric eosinophilic esophagitis

NV Hoffmann, K Keeley, JB Wechsler - Clinical Gastroenterology and …, 2023 - Elsevier
… to esophageal dysfunction. We aimed to assess whether esophageal distensibility has utility
… severity in a cohort of pediatric patients with EoE with symptoms of esophageal dysfunction. …

The severity of reduced esophageal distensibility parallels eosinophilic esophagitis disease duration

IK Araujo, C Shehata, I Hirano, N Gonsalves… - Clinical …, 2024 - Elsevier
… This study aimed to demonstrate the changes in esophageal distensibility relative to duration
… clinical characteristics associated with progressive reduction in esophageal distensibility. …

Mechanical properties of the esophagus in eosinophilic esophagitis

MA Kwiatek, I Hirano, PJ Kahrilas, J Rothe, D Luger… - Gastroenterology, 2011 - Elsevier
… The goal of this study was to measure and compare esophageal distensibility in EoE …
whether esophageal distensibility was correlated with the degree of eosinophilic infiltration or …

Evaluation of esophageal distensibility in eosinophilic esophagitis: an update and comparison of functional lumen imaging probe analytic methods

DA Carlson, Z Lin, I Hirano, N Gonsalves… - …, 2016 - Wiley Online Library
… was that quantitation of esophageal distensibility using the FLIP … esophageal contractility.
In addition, we described updated analytic methods to evaluate esophageal body distensibility

Clinical relevance of esophageal subepithelial activity in eosinophilic esophagitis

I Hirano - Journal of Gastroenterology, 2020 - Springer
… The lack of correlation between esophageal distensibility and mucosal eosinophil density
provides several potential insights into EoE disease mechanisms. Although epithelial …

Esophageal dysmotility is associated with disease severity in eosinophilic esophagitis

DA Carlson, C Shehata, N Gonsalves, I Hirano… - Clinical …, 2022 - Elsevier
… of eosinophilic esophagitis (EoE) with esophageal dysmotility … , including esophageal
distensibility, associated with … had reduced esophageal distensibility (distensibility plateau <17 …