A phenotypic analysis shows that eosinophilic esophagitis is a progressive fibrostenotic disease

ES Dellon, HP Kim, SLW Sperry, DA Rybnicek… - Gastrointestinal …, 2014 - Elsevier
fibrostenotic phenotype more than doubles. The predicted probability of developing a fibrostenotic
EoE phenotype … as a predictor of a mixed or fibrostenotic phenotype were 3.07 (95% CI…

[HTML][HTML] Progression from an inflammatory to a fibrostenotic phenotype in eosinophilic esophagitis

NT Koutlas, ES Dellon - Case reports in gastroenterology, 2017 - karger.com
… a fibrostenotic phenotype of EoE in the absence of treatment. At the time of diagnosis, none
of the patients had significant evidence of fibrostenosis, … to fibrostenotic phenotypes of EoE in …

Early comparison of inflammatory vs. fibrostenotic phenotype in eosinophilic esophagitis in a multicenter longitudinal study

MB Singla, M Chehade, D Brizuela… - Clinical and …, 2015 - journals.lww.com
… We also compared fibrostenotic and mixed phenotypes to … to limit our phenotypes to only
inflammatory and fibrostenosis, similar … comparing fibrostenotic patients to a mixed phenotype (…

Outcomes of esophageal dilation in eosinophilic esophagitis: safety, efficacy, and persistence of the fibrostenotic phenotype

TM Runge, S Eluri, CC Cotton, CM Burk… - Official journal of the …, 2016 - journals.lww.com
phenotype. Other studies suggest that repeated dilations over an “induction” period are
needed for patients with severe fibrostenoticphenotypes of EoE patients would better practice. …

Phenotypes and endotypes in eosinophilic esophagitis

MA Ruffner, A Cianferoni - Annals of Allergy, Asthma & Immunology, 2020 - Elsevier
… The odds of developing fibrostenosis increased 5% for each year of symptoms before …
phenotype, whereas older patients present with a fibrostenotic phenotype, with risk of fibrostenosis

A physiomechanical model of esophageal function in eosinophilic esophagitis

DA Carlson, I Hirano, N Gonsalves, PJ Kahrilas… - Gastroenterology, 2023 - Elsevier
… inflammation, but also heterogeneous presentations involving fibrostenotic esophageal
remodeling and esophageal dysmotility. We aimed to define and evaluate phenotypes of EoE …

[HTML][HTML] Fibrostenotic eosinophilic esophagitis phenotype is defined by a proliferative gene signature

C Menard-Katcher, C Liu, MD Galbraith, T Benson… - Allergy, 2023 - ncbi.nlm.nih.gov
Eosinophilic Esophagitis (EoE) is a chronic inflammatory esophageal disease in which a …
This fibrostenotic EoE (FS-EoE) phenotype is defined by the presence of esophageal strictures …

Narrowing the focus on fibrostenotic eosinophilic esophagitis

SM Lagana, JA Abrams - Gastrointestinal Endoscopy, 2014 - giejournal.org
phenotype fell somewhere in between, but overall it resembled more closely the fibrostenotic
phenotype. … of EoE for the mixed and fibrostenotic phenotypes (8 years for each group) was …

Eosinophils in eosinophilic esophagitis: the road to fibrostenosis is paved with good intentions

AD Doyle, MY Masuda, H Kita, BL Wright - Frontiers in immunology, 2020 - frontiersin.org
… Seasonal exacerbation of esophageal eosinophilia in children with eosinophilic esophagitis
and allergic rhinitis. Ann Allergy Asthma Immunol (2015) 115(3):224–8 e1. doi: 10.1016/j.…

Understanding fibrosis in eosinophilic esophagitis: are we there yet?

J Armbruster-Lee, CP Cavender… - Journal of Leukocyte …, 2018 - academic.oup.com
… Confirmatory diagnosis requires histologic analysis with deep esophageal biopsies, although
there is a fibrostenotic phenotype diagnosed by visual changes seen on endoscopy.6,30 …