DNA methylation-based age clocks: From age prediction to age reversion

R Noroozi, S Ghafouri-Fard, A Pisarek… - Ageing Research …, 2021 - Elsevier
… potential of estimated epigenetic age acceleration regarding … the revealed age-related
epigenetic changes, the recent age-… epigenetic age estimator (epigenetic age clock), epigenetic

Epigenetic age prediction

DJ Simpson, T Chandra - Aging cell, 2021 - Wiley Online Library
… of age predictors utilising DNA methylation have been developed, referred to as epigenetic
… While they appear to estimate biological age, it remains unclear whether the methylation

Association of facial ageing with DNA methylation and epigenetic age predictions

RE Marioni, DW Belsky, IJ Deary, W Wagner - Clinical Epigenetics, 2018 - Springer
… the hypothesis that an epigenetic predictor for biological age might be trained on face-age
as a surrogate for biological age rather than on chronological age. Our data demonstrate that …

New targeted approaches for epigenetic age predictions

Y Han, J Franzen, T Stiehl, M Gobs, CC Kuo, M Nikolić… - BMC biology, 2020 - Springer
… Targeted DNA methylation analysis at few age-associated … of epigenetic age-predictions.
Furthermore, we demonstrate that the stochastic evolution of age-associated DNA methylation

Epigenetic aging: Biological age prediction and informing a mechanistic theory of aging

A Li, Z Koch, T Ideker - Journal of internal medicine, 2022 - Wiley Online Library
… Numerous studies have shown that epigenetic age—an individual's degree of aging based
on patterns of DNA methylation—can be computed and is associated with an array of factors …

Epigenetic predictor of age

S Bocklandt, W Lin, ME Sehl, FJ Sánchez… - PloS one, 2011 - journals.plos.org
… Based on this observation, we were able to build a model that can predict the age of a subject
based on the methylation status of just two cytosines in the genome, explaining 73% of the …

DNA methylation-based biomarkers and the epigenetic clock theory of ageing

S Horvath, K Raj - Nature reviews genetics, 2018 - nature.com
… selects the most informative CpGs for the age prediction or estimation model. Thus, the …
algorithm that incorporates the DNA methylation levels into an age estimate. Many of the CpGs …

Role of DNA methylation in human age prediction

N Goel, P Karir, VK Garg - Mechanisms of ageing and development, 2017 - Elsevier
… Paired T-test, R, Kruskal-Wallis test – This study proves that DNA of the cerebellum is stable
at epigenetic level and needs less maintenance. The rate of aging in the cerebellum is slow …

[HTML][HTML] Epigenetic-aging-signature to determine age in different tissues

CM Koch, W Wagner - Aging (Albany NY), 2011 - ncbi.nlm.nih.gov
… – and they might facilitate age-predictions in heterogeneous cell preparations. …
methylation datasets to elaborate an Epigenetic-Aging-Signature which can be used for age-predictions

Refining epigenetic prediction of chronological and biological age

E Bernabeu, DL McCartney, DA Gadd, RF Hillary… - Genome Medicine, 2023 - Springer
… Next, to create a cAge predictor, we use methylation data from 24,674 participants from the
Generation Scotland study, the Lothian Birth Cohorts (LBC) of 1921 and 1936, and 8 other …