Epigenetic mechanisms in neurological disease

M Jakovcevski, S Akbarian - Nature medicine, 2012 - nature.com
… The exploration of brain epigenomes, which consist of various types of … mechanisms of
neural development, neurological disease and aging. Traditionally, chromatin defects in the brain

Epigenetic mechanisms during ageing and neurogenesis as novel therapeutic avenues in human brain disorders

R Delgado-Morales, RC Agís-Balboa, M Esteller… - … epigenetics, 2017 - Springer
epigenetically deregulated in human neurological disorders, in this review, we have focused
on the potential use of epigenetic … ageing and especially in neurological disorders. We will …

Epigenetic mechanisms in neurological and neurodegenerative diseases

J Landgrave-Gómez, O Mercado-Gómez… - Frontiers in cellular …, 2015 - frontiersin.org
epigenetic mechanisms in the function and homeostasis of the CNS and their participation in
a variety of neurological disorders. … in processes involved in neurological disorders such as …

Diverse epigenetic mechanisms of human disease

E Brookes, Y Shi - Annual review of genetics, 2014 - annualreviews.org
… an overview of the disparate epigenetic mechanisms that cause human disease ( Figure 1 ).
… to exert their influences on human health through epigenetic mechanisms. These mutations …

Epigenetic mechanisms underlying human epileptic disorders and the process of epileptogenesis

IA Qureshi, MF Mehler - Neurobiology of disease, 2010 - Elsevier
… Although, to our knowledge, the importance of epigenetic mechanisms in epilepsy has not
been previously discussed systematically or in detail. In this review, we highlight evidence …

Epigenetic mechanisms in human disease

AP Feinberg, M Oshimura, JC Barrett - 2002 - AACR
… studying epigenetic mechanisms in development and disease. To our knowledge, it was
the first such conference that addressed epigenetic mechanisms of human disease generally, …

Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies

RG Urdinguio, JV Sanchez-Mut, M Esteller - The Lancet Neurology, 2009 - thelancet.com
… , and Huntington's disease, and in other neurological disorders such as multiple … epigenetic
changes present in neurological diseases and discuss the therapeutic potential of epigenetic

An introduction to epigenetic mechanisms

EJ Radford - Progress in molecular biology and translational …, 2018 - Elsevier
… of epigenetic mechanisms, and I will briefly discuss some of the known neurodevelopmental
disorders … As most neurons, particularly in the human brain, are post-mitotic, there is also …

Epigenetic mechanisms in the context of complex diseases

J Van Vliet, NA Oates, E Whitelaw - Cellular and molecular life sciences, 2007 - Springer
… Another challenge facing researchers is the difficultly of accessing relevant tissue samples,
such as from the human brain. Despite this, epigenetic research on humans holds the …

Epigenetic approaches to psychiatric disorders

C Ptak, A Petronis - Dialogues in clinical neuroscience, 2010 - Taylor & Francis
… (AD), Citation20 autism, Citation21 and bipolar disorder (BD). Citation22 Genomic imprinting,
an epigenetic mechanism in which differential epigenetic modification of genes occurs …