Epigenetic mechanisms of neurodegenerative diseases and acute brain injury

MJ Bertogliat, KC Morris-Blanco… - Neurochemistry …, 2020 - Elsevier
Epigenetic modifications are emerging as major players in the pathogenesis of
neurodegenerative disorders and susceptibility to acute brain injury. DNA and histone
modifications act together with non-coding RNAs to form a complex gene expression
machinery that adapts the brain to environmental stressors and injury response. These
modifications influence cell-level operations like neurogenesis and DNA repair to large,
intricate processes such as brain patterning, memory formation, motor function and …
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