Metabolic reprogramming and epigenetic modifications on the path to cancer

L Sun, H Zhang, P Gao - Protein & cell, 2022 - academic.oup.com
… In this review, we focus on how metabolic reprogramming of tumor cells and immune
cells reshapes epigenetic alterations, in particular the acetylation and methylation of histone

Metabolic reprogramming and epigenetic modifications in cancer: from the impacts and mechanisms to the treatment potential

X Xu, Q Peng, X Jiang, S Tan, Y Yang… - … & Molecular Medicine, 2023 - nature.com
… , histone modification, chromatin remodeling, and noncoding RNA on metabolic reprogramming
… the treatment of tumors based on metabolic reprogramming and epigenetic modification. …

Epigenetic reprogramming in metabolic disorders: nutritional factors and beyond

Z Cheng, L Zheng, FA Almeida - The Journal of nutritional biochemistry, 2018 - Elsevier
… in metabolic activity and pathways have been increasingly associated with altered DNA
methylation, histone modification … can reverse the epigenetic and metabolic changes. Here we …

Reciprocal regulation of metabolic reprogramming and epigenetic modifications in cancer

X Yu, R Ma, Y Wu, Y Zhai, S Li - Frontiers in Genetics, 2018 - frontiersin.org
… One major function is regulating epigenetic modifications to … that epigenetic modifications
could in turn alter metabolism in … connection between metabolic and epigenetic rewiring in …

Metabolic reprogramming of stem cell epigenetics

JG Ryall, T Cliff, S Dalton, V Sartorelli - Cell stem cell, 2015 - cell.com
… reactions leading to epigenetic modifications and transcriptional regulation. We discuss how
metabolic reprogramming” contributes to global epigenetic changes in the context of naive …

Fetal metabolic programming and epigenetic modifications: a systems biology approach

S Sookoian, TF Gianotti, AL Burgueño, CJ Pirola - Pediatric research, 2013 - nature.com
… , such as the role of microRNAs (miRNAs) in the regulation of fetal metabolic programming.
… complex metabolic networks may be perturbed by genomic and epigenetic changes and how …

Metabolic controls on epigenetic reprogramming in regulatory T cells

J Lu, Y Liang, H Meng, A Zhang, J Zhao… - Frontiers in …, 2021 - frontiersin.org
… knowledge of metabolic reprogramming and epigenetic features in Treg cells within different
contexts. We then discuss how metabolism controls epigenetic modification and evaluate …

The complex interplay between metabolic reprogramming and epigenetic alterations in renal cell carcinoma

A Lameirinhas, V Miranda-Gonçalves, R Henrique… - Genes, 2019 - mdpi.com
… and epigenetic alterations disclosed by RCC that have been implicated in aberrant tumor
metabolism… Furthermore, the interactions between intracellular metabolites and epigenetic

Epigenetic programming and fetal metabolic programming

Z Zhu, F Cao, X Li - Frontiers in endocrinology, 2019 - frontiersin.org
… induce the development of metabolic syndrome in adult … of epigenetic programming in
fetal metabolic programming. … of epigenetic modification in fetal metabolic programming (77…

Lactylation, a novel metabolic reprogramming code: current status and prospects

AN Chen, Y Luo, YH Yang, JT Fu, XM Geng… - Frontiers in …, 2021 - frontiersin.org
… advances in a novel lactate-induced histone modification, histone lysine lactylation. These
observations support the idea that epigenetic reprogramming-linked lactate input is related to …