… , that the response to IFN-λ involves primarily epithelial cells, at least in the kidney and in the
… response to IFN-λ was notably prominent in cells of the pluristratifiated urinary epithelium. In …

… , we demonstrate that intestinal epithelial cells, which are the prime target cells of rotavirus,
strongly responded to IFN-λ but only marginally to type I IFN in vivo. Systemic treatment of …

… predominantly induced by IFN-λ 2 . We confirm the influence of epithelial cell polarization for
… predominantly IFN-λ 2 -induced genes in the gut epithelium in vivo. Our results suggest that …

… epithelial cells (AECs) and the consequences of TLR agonist stimulation for the production of
type I (IFN-α/β) and type III (IFN-λ) … First, in order to validate our in vitro model, we examined …

… A defect in the ability of asthmatic bronchial epithelial cells (BECs) to produce IFN-β, IFN-λ, …
doses in our in vitro model with those required in vivo because delivery of IFN-β into the …

… In PBMCs interferon-α, interferon-β and interferon-λ mRNAs … epithelial cells (BECs) from
asthmatic subjects exposed to RV in vitro had profoundly impaired production of interferon (IFN)-…

… epithelial cell lines and, to a less extent, murine in vivo analyses, have revealed that interferon-γ
(IFN-γ) can increase epithelial … epithelial permeability and then focus on the ability of IFN…

… that lung epithelial cells abundantly express functional IFN-λ … Epithelial cells of the intestine
express functional IFN-λ … to in vivo electroporation of a plasmid encoding mouse IFN-λ3 was …

… IFN-L toward controlling the infection of PEDV in vitro. IFN-L preferentially acts on epithelial
cells because IFNLR1 is expressed primarily on the epithelial cells of the gastrointestinal …

… epithelial cells do not express functional receptors for IFN-α/β. We further demonstrate that
virus-infected intestinal epithelial cells are potent producers of IFN-λ, … for in vivo IFN treatment, …