Bioinformatics approach for the construction of multiple epitope vaccine against omicron variant of SARS-CoV-2

S Zaib, F Akram, ST Liaqat, MZ Altaf, I Khan… - Scientific Reports, 2022 - nature.com
… shots of vaccines are necessary. If a person is exposed to SARS-CoV-2 or its variants, antibodies
produced by vaccination … multi-epitope vaccine of omicron variant using bioinformatics …

[HTML][HTML] Immunoinformatic approach for the construction of multi-epitopes vaccine against omicron COVID-19 variant

K Khan, SA Khan, K Jalal, Z Ul-Haq, R Uddin - Virology, 2022 - Elsevier
… in several countries because of Omicron variant, and it is … effective vaccination that can
tackle Omicron SARS-CoV-2 variantsvaccine that may potentially battle SARS-CoV-2 Omicron

A novel vaccine based on SARS-CoV-2 CD4+ and CD8+ T cell conserved epitopes from variants Alpha to Omicron

I Palatnik-de-Sousa, ZS Wallace, SC Cavalcante… - Scientific reports, 2022 - nature.com
… to assess conservancy of epitopes. The sequence of all variants, from Alpha to Omicron,
were not aligned as they were in our investigation. They report a list of 10 Class II epitopes of M, …

Identification of vaccine candidate against Omicron variant of SARS-CoV-2 using immunoinformatic approaches

Aasim, R Sharma, CR Patil, A Kumar, K Sharma - In Silico Pharmacology, 2022 - Springer
… the design of vaccine candidates against the Omicron variant. … designed a vaccine candidate
against the Omicron variant (B.… (As Omicron variant spike protein) was taken for our epitope

SARS-CoV-2 Delta and Omicron variants evade population antibody response by mutations in a single spike epitope

P He, B Liu, X Gao, Q Yan, R Pei, J Sun, Q Chen… - Nature …, 2022 - nature.com
epitope location, neutralization mechanism and analysis of antibody binding to spike variants
by natural infection and vaccination, numerous SARS-CoV-2 variants have emerged, these …

Designing multi-epitope based peptide vaccine targeting spike protein SARS-CoV-2 B1. 1.529 (Omicron) variant using computational approaches

M Parmar, R Thumar, J Sheth, D Patel - Structural Chemistry, 2022 - Springer
… Some variants may evade the current vaccines. This study was carried out because of
the rapid rise of the omicron variant and its fear of eluding the vaccine. Traditional vaccine

Design of a multi-epitope-based peptide vaccine against the SARS-CoV-2 Omicron variant using bioinformatics approach

E Roohparvar Basmenj, B Omidvar… - Journal of …, 2023 - Taylor & Francis
Omicron variant of SARS-CoV-2 and identify potential immunogenic epitopes in order to design
multi-epitope vaccine … This article asserts that the vaccine presented in this study has the …

T cell epitopes in SARS-CoV-2 proteins are substantially conserved in the Omicron variant

SJ Choi, DU Kim, JY Noh, S Kim, SH Park… - Cellular & molecular …, 2022 - nature.com
… induced by COVID-19 vaccination or natural infection [1,2,3], … epitopes are considerably
conserved in the Omicron variant … -19 vaccination or natural infection respond to the Omicron

Shared N417-dependent epitope on the SARS-CoV-2 omicron, beta, and delta plus variants

T Moyo-Gwete, M Madzivhandila, NN Mkhize… - Journal of …, 2022 - Am Soc Microbiol
… to target in future vaccines and therapeutics. … of variants into “serotypes” or “clusters,” we
show that the antibody response toward different variants can converge on shared epitopes. …

Omicron-included mutation-induced changes in epitopes of SARS-CoV-2 spike protein and effectiveness assessments of current antibodies

D Guo, H Duan, Y Cheng, Y Wang, J Hu, H Shi - Molecular Biomedicine, 2022 - Springer
… numerous variant strains, how to select effective vaccines and … , and only D405 and K417
epitopes are defined as weak … and Omicron variants, and by Thr in the Omicron variant, …