Potential therapeutic applications of extracellular vesicles in the immunopathogenesis of COVID-19

M Motallebnezhad, M Omraninava, HEG Ghaleh… - … -Research and Practice, 2023 - Elsevier
… underlying the pathogenesis of SARS-CoV-2 may contribute to discovering a novel potential
therapeutic approach to the management of COVID-19. Recently, extracellular vesicle (EV)-…

The potential role of extracellular vesicles in COVID-19 treatment: opportunity and challenge

Y Yan, W Zhou, Y Wang, Q Guo, F Zhao… - Frontiers in Molecular …, 2021 - frontiersin.org
… , some approaches using extracellular vesicles (EVs) are emerging. In this review, we
summarize current prevalence and pathogenesis of COVID-19, involving the combination of SARS…

[HTML][HTML] The potential role of extracellular vesicles in COVID-19 associated endothelial injury and pro-inflammation

B Krishnamachary, C Cook, L Spikes, P Chalise… - medRxiv, 2020 - ncbi.nlm.nih.gov
Extracellular vesicles play a key role in the pathogenesis of various diseases, including
acute respiratory distress syndrome (ARDS), chronic obstructive pulmonary disease (COPD) …

Extracellular vesicle‐mediated endothelial apoptosis and EV‐associated proteins correlate with COVID19 disease severity

B Krishnamachary, C Cook, A Kumar… - … extracellular vesicles, 2021 - Wiley Online Library
… In conclusion, our findings support a role for EVs in the pathogenesis of COVID-19 disease
and underpin the development of EV-based approaches to predicting disease severity, …

[PDF][PDF] Serum‐derived extracellular vesicles: Novel biomarkers reflecting the disease severity of COVID19 patients

T Tertel, S Tomić, J Đokić, D Radojević… - … of Extracellular …, 2022 - Wiley Online Library
immunopathogenesis in COVID-19. Altogether, our results support the potential of serum EVs
as powerful biomarkers for COVID-19 … to unravel the role of EVs in COVID-19 progression. …

Genomic communication via circulating extracellular vesicles and long-term health consequences of COVID-19

S Nair, E Nova-Lamperti, G Labarca… - Journal of Translational …, 2023 - Springer
… and change in the molecular cargo of extracellular vesicles (EVs). EVs are vesicles released
… EVs and their potential role in COVID-19 pathogenesis, their current and future implications …

Activated platelets and platelet-derived extracellular vesicles mediate COVID-19-associated immunothrombosis

M Ebeyer-Masotta, T Eichhorn, R Weiss… - Frontiers in Cell and …, 2022 - frontiersin.org
… + extracellular vesicles promote neutrophil activation, resulting in the release of neutrophil
extracellular … platelet-derived EVs in the pathogenesis of immunothrombosis, and we discuss …

[HTML][HTML] Role of neutrophils, platelets, and extracellular vesicles and their interactions in COVID19‐associated thrombopathy

A Caillon, A Trimaille, J Favre, L Jesel, O Morel… - Journal of Thrombosis …, 2022 - Elsevier
… a higher NET density in COVID19 versus non COVID19 patients. The histology of thrombi
… a role of NETs in the pathogenesis of myocardial infarction during COVID19. Several other …

The role of extracellular vesicles in COVID-19 virus infection

M Hassanpour, J Rezaie, M Nouri, Y Panahi - Infection, Genetics and …, 2020 - Elsevier
… Exosome-based strategies for the treatment of COVID-19 virus infection … COVID-19 virus
infection. Understanding molecular mechanisms behind extracellular vesicles related COVID-19

Allogenic mesenchymal stromal cells and their extracellular vesicles in COVID-19 induced ARDS: a randomized controlled trial

M Zarrabi, MA Shahrbaf, M Nouri, F Shekari… - Stem Cell Research & …, 2023 - Springer
… with severe Coronavirus disease-2019 (COVID-19) are acute … and their derived extracellular
vesicles in COVID-19 patients. … pathogenesis of COVID-19 were not evaluated in this study. …