… The standardization of manufacturing and robust quality control must meet all the Food and
Drug Administration requirements and expectations. We believe the evolution of EV research …

… ), and (iii) Plasma/serum quality control (items 3.0–3.27, Supplementary File 1). Since quality
controls are the key to monitoring the quality of the prepared plasma and serum samples, …

… The characterization of circulating extracellular vesicles (EVs… an additional layer in
mitochondrial quality control. Indeed, … trafficking in the setting of mitochondrial quality control; and …

… For this reason, the quality of EVs must be ensured via the quality control of the raw materials
and the control of the manufacturing processes, in addition to controlling the final product (…

… Extracellular vesicles (EVs) have sparked tremendous interest owing to their prominent … ,
here we report a new benchmark to the quality and efficiency assessment of EVs isolated from …

… EV research can be broadly divided into 3 categories, each of which mandates a different
level of quality control and operating procedure. Since many technical protocols exist, some …

… and/or subpopulations thereof, and store and use aliquots of EV preparations for complementary
characterization, including quality control and further downstream application (Fig. 2a). …

… and downstream processing, as well as quality controls. Since proposed measures of EV …
use and can be used for a reasonable Quality Control (QC) strategy of the novel EV product. …

… Such quality control analysis is vital to ensure the validity of the studies of biological functions
and disease biomarkers associated with EVs. It is important to note that given the fact that …

… analysis, as standard qRT-PCR depends on normalization to the expression of levels of
endogenous controls, and in the case of vesicle-derived RNAs such controls are not ubiquitous. …