… Resistance to activated protein C (APC) is a common inherited risk factor for venous … We
conclude that APC resistance caused by homozygous factor V Leiden leads to a high risk of …

… of resistance to activated protein C and the factor V Leiden … Factor V Leiden is the most
common genetic abnormality … the factor V Leiden mutation show phenotypic resistance to …

… the factor V gene within the UK population: relationship to activated protein C resistance and
… ) A possible role for activated protein C resistance in patients with first and second trimester …

… It is caused by a single nucleotide substitution resulting in an R506Q missense mutation,
resulting in factor V resistance to activated protein C (APC) inactivation. Carriers of FVL have …

… Activated protein C inhibits coagulation through the inactivation of membrane-bound
activated factor V and activated factor VIII. Activated protein C resistance results in …

… Background: Activated protein C (APC) resistance with or without factor V Leiden (FVL) is
a … protein C (APC) resistance was described from Malmö in 1993 as a novel risk factor of …

… protein C/protein S pathway, the significance of activated protein C resistance and the factor
V Leiden … used to detect activated protein C resistance and the factor V Leiden mutation. A …

… OBJECTIVE: Our purpose was to evaluate activated protein C resistance … , protein C,
protein S, antithrombin III, functional test for activated protein C resistance, and factor V Leiden …

… to activated protein C (APC) in the absence of factor V Leiden mutation. Using a Kaplan–Meier
analysis, a significantly higher proportion of patients with APC resistance developed DVT …

… Activated protein C resistance assays can detect factor V Leiden with high accuracy,
depending on the method used. Factor Xa inhibitors such as rivaroxaban and direct thrombin …