… Because fatty acids are the building blocks of these important lipids, fatty acid synthase (FASN)
emerges as a unique oncologic target. FASN inhibitors are being studied preclinically …

… of n-3 polyunsaturated fatty acid (… molecular pathways and bioactive metabolites, effects on
specific clinical endpoints, and existing dietary guidelines. Major dietary sources include fatty …

… toxic free fatty acids associated with insulin resistance-induced massive free fatty acid
mobilization from adipose tissue and the increased de novo hepatic fatty acid synthesis from …

… Nowadays, a more complex model suggests that fatty acids (FAs) and their metabolites may
be … This review discusses the molecular mechanisms that underlie the pathophysiological …

… The pathway for FA biosynthesis is highly conserved within … pathway. In animals and fungi,
all steps of FA biosynthesis involve one multifunctional protein complex, the type-I fatty acid …

… (EPA) and docosahexaenoic acid (DHA) may modify the risk and … this fatty acid in infant
blood improving their mental development. The potential mechanisms by which these fatty acids …

… Nutrient supply and cellular energy demands are constantly changing, so the molecular …
chain fatty acids across the plasma membrane–lipid rafts and fatty acid transport proteins. …

… fatty acids. Accumulated evidence, as discussed in this review, suggests that dietary fatty acids
can regulate signaling pathways … of receptor-mediated signaling pathways (eg, G proteins …

… Together, it becomes clear now that multiple steps in various receptor-mediatedsignaling
pathways can be modulated by dietary fatty acids. It will be achallenging task to quantitatively …

… Here, we have gathered the main molecular pathways connecting adipose tissue (AT) and
adipocytes with cancer cells in the tumor microenvironment, as well as their impact on cancer …