… the roles of Fc-dependent antibody effector functions in the context of SARS-CoV-2 infection,
… these data for the development of next-generation SARS-CoV-2 vaccines and therapeutics. …

… (mAbs) in SARS-CoV-2-infected animals. Whereas Fc effector functions are dispensable when
… When given after infection, intact mAbs reduce SARS-CoV-2 burden and lung disease in …

… SARS-CoV-2 antibody programs have chosen to use Fc … In addition, we assessed the impact
of Fc functionality on its … demonstrated that the engagement of Fc receptors by SC31 trigger …

… between Fc effector functions and … Fc effector functions to control SARS-CoV-2 infection.
The antiviral activity of passively transferred immune serum was lost against multiple SARS-CoV-…

… Thus, we aimed to define whether Fc effector functions were equally disrupted across
VOCs. Given the ability of VOCs to re-infect previously naturally immune individuals ( …

… -CoV and SARS-CoV-2, … SARS-CoV-2, the seventh coronavirus known to infect humans,
is a member of the Betacoronavirus genus, which includes the highly pathogenic SARS-CoV …

… , Fc effector function escape from VOCs is poorly defined. Furthermore, whether VOCs trigger
Fc functions … Here, we demonstrate that the Beta VOC partially evades Fc effector activity in …

… in SARS-CoV-2 naive individuals but strong anti-receptor binding domain and spike antibodies
with Fc-mediated effector … Our results highlight the potential role of Fc-mediated effector …

… Fc-effector functions. Here, we review these assays and what is known regarding anti-SARS-CoV-2
Fc-effector func… state of knowledge regarding anti-SARS-CoV-2 Fc-effector functions. …

… Fc-effector activity, in contrast to those with poor Fc function, delay mortality and/or
improve survival of SARS-CoV-… Finally, despite reduced neutralization, ancestral SARS-CoV-2-elicited …