Identification of noninvasive diagnostic biomarkers for hepatocellular carcinoma by urinary proteomics

Y Zhao, Y Li, W Liu, S Xing, D Wang, J Chen, L Sun… - … of proteomics, 2020 - Elsevier
… MRM, and the integration of the features also worked well in the MRM dataset. This is the
first time that urinary proteomic strategy was applied in discovering HCC biomarkers from high-…

Mass spectrometry‐based tear proteomics for noninvasive biomarker discovery

E Ponzini, C Santambrogio, A De Palma… - Mass Spectrometry …, 2022 - Wiley Online Library
… MS-based proteomics of body fluids has strongly impacted the field of biomarker discovery
for … This field still awaits effective integration with individual profiling at the transcriptome and …

The role of proteomics in biomarker development for improved patient diagnosis and clinical decision making in prostate cancer

CL Tonry, E Leacy, C Raso, SP Finn, J Armstrong… - Diagnostics, 2016 - mdpi.com
… in identifying biomarkers of clinical utility. Here, we provide a comprehensive overview of
the application of proteomics to the discovery and development of protein biomarkers and their …

Pathology, proteomics and the pathway to personalised medicine

P Jin, J Lan, K Wang, MS Baker, C Huang… - … review of proteomics, 2018 - Taylor & Francis
… the application of proteomics for development and translation of biomarkers for disease-…
Robust proteomics technologies integrated with efficient data analysis and patient records …

Integrated proteomics sample preparation and fractionation: Method development and applications

X Ye, J Tang, Y Mao, X Lu, Y Yang, W Chen… - TrAC Trends in …, 2019 - Elsevier
… exciting technology development for integrated proteomics sample preparation and peptide
… of the whole proteomics workflow for in vivo proteomics and clinical proteomics. In this review…

Artificial intelligence for proteomics and biomarker discovery

M Mann, C Kumar, WF Zeng, MT Strauss - Cell systems, 2021 - cell.com
… MS)-based proteomics and … proteomics than they are in deep-sequencing-based technologies
and much progress can still be made. We describe data integration of different proteomics

An integrated proteomic and peptidomic assessment of the normal human urinome

A Di Meo, I Batruch, AG Yousef, MD Pasic… - Clinical Chemistry and …, 2017 - degruyter.com
… In total, we identified 2091 non-redundant proteins by combining proteomic and … integrated
proteomic and peptidomic analysis. The inter-individual CV value was 0.65 for our integrated

Proteomic studies of cerebrospinal fluid biomarkers of Alzheimer's disease: an update

E Portelius, G Brinkmalm, J Pannee… - … review of proteomics, 2017 - Taylor & Francis
… An integrated proteomic and endopeptidomic approach based on TMT labeling that enabled
analysis of proteins and endogenous peptides to be performed on the same sample aliquot …

Proteomics-driven cancer biomarker discovery: looking to the future

RJ Simpson, OK Bernhard, DW Greening… - Current opinion in …, 2008 - Elsevier
… In this context, much effort has been directed toward integration of … proteomics technologies
limit our capacity to directly interrogate the blood proteome for the purpose of biomarker

Proteomic profiling from human samples: the body fluid alternative

S Kennedy - Toxicology letters, 2001 - Elsevier
Proteomics is one of the technologies rapidly changing our approach to drug development.
The applications of proteomics, particularly with reference to analysis of body fluid samples, …