… We sought to identify biomarkers from biochemical, metabolic and proteomic screens that …
An integrative multi-variate approach was applied to the analysis of cerebrospinal fluid …

… Research of differential Omics accelerate the advancements of biomarkers’ discovery. By …
, integrative system biology creates predictive models of cells, organs, biochemical processes …

… Alzheimer’s disease (AD) lacks protein biomarkers reflective of its diverse underlying … Here,
we used integrative proteomics to identify cerebrospinal fluid (CSF) biomarkers representing …

… In this model, various factors are integrated: the interaction and … This integrative understanding
may lead to new hypotheses … An integrated, system-level understanding of a biomarker (…

… Peripheral biochemical monitoring involves the use of … of analytes in biofluids such as
interstitial fluid, saliva, tears and … in interstitial fluid, and device-integrated sweat stimulation for …

… fluid biomarkers. CSF-level elevation was confirmed in AD and asymptomatic AD for several
proteins pertaining to this module related to astrocyte and microglial metabolism. In another …

… In this review paper, we aim to summarize recent biomarker discovery research focusing on
… There is also a need for integrative approaches that enables multi-modal biomarker analysis …

… The word ‘biomarker’ has been used extensively across therapeutic areas and many … ,
biochemical, developmental, morphological and molecular measures. In drug trials, biomarkers …

… the art for the latest fluid biomarkers of AD, Parkinson… fluid biomarkers in major NDDs is an
effort that goes beyond the scope of this paper. We focused on the most promising biomarkers …

… Understanding biochemical changes and new biomarkers for MCI may provide a better …
have also revealed new biomarkers for AD [17,18]. Furthermore, integrated metabolomic and …