… cell senescence in the pathogenesis of neurodegenerative diseases and in brain tumours. A
better understanding of senescence … senescence therapies against these brain pathologies. …

… Here, we review evidence of cellular senescence in neurons and glial cells and we discuss
… a role for cellular senescence in neurodegeneration, with special focus on AD, PD and MS. …

… While senescent cells in peripheral tissues have been the focus of numerous recent studies,
their involvement in or contribution to cognitive decline with aging or diseases of the central …

… a senescent state remains unclear. In this review we examine recent data that suggest that
cellular senescence … and those phenotypes observed in cellular senescence, leading us to …

… cellular senescence in the neurodegenerative diseases AD, Down syndrome (DS), and PD.
… that demonstrate the role of cellular senescence in the neurodegenerative diseases AD, DS, …

… Decreasing senescent cell abundance … cells, alleviates neurodegenerative diseases in
preclinical models. In this review, we consider roles of senescent cells in neurodegenerative …

… discuss how cellular senescence contributes to brain aging and neurodegenerative diseases,
… Much of the focus on developing senescence-related drugs is on eliminating long-lasting …

… into a non-deleterious phenotype by preventing the SASP without killing the senescent
cells themselves. In this review we will focus on senolytics; for a description of senomorphics …

… has been reviewed extensively elsewhere (Campisi et al., 2011; Lujambio, 2016; Rhinn et
al., 2019; van Deursen, 2014), we will focus on the role of chronic senescence in brain aging …

… cause changes in models of neurodegeneration similar to those … role of senescent microglia
in neurodegenerative diseases. … Historically, most observations of microglia have focused on …